PEMANFAATAN LIMBAH KULIT BUAH SALAK PONDOH (Salaccae edulis Reinw) MENJADI SEDIAAN SAMPO DAN AKTIVITASNYA TERHADAP Staphylococcus epidermidis DAN Candida albicans

  • Yuyun Sri Wahyuni Universitas Muhammadiyah Makassar
  • Hernawati Basir Universitas Muhammadiyah Makassar
  • Riskayanti Puspita Sari Akademi Farmasi Yamasi Makassar
  • Asamaul Husna Akademi Farmasi Yamasi Makassar

Abstract

In South Sulawesi Province, the pondoh salak plant is widely used as medicine. Many people only eat the fruit and throw away the skin, because they consider the skin of the Pondoh salak fruit to be useless. Pondoh salak fruit skin contains flavonoids, saponins, tannins, phenols, terpenoids and alkaloids. The saponin content functions as a foam maker and flavonoids function to accelerate hair growth. This research aims to make a shampoo preparation from the ethanol extract of Pondoh salak fruit peel (Salacca edulis Reinw) and test the stability of the shampoo and test the activity of the shampoo preparation of Pondoh salak fruit peel ethanol extract (Salacca edulis Reinw) on the growth of Staphylococcus epidermidis and Candida albicans. This research used laboratory experimental methods, formulating shampoo from ethanol extract of pondoh salak fruit peel (Salacca edulis Reinw) into four formulations with respective concentrations, namely F0: 0%, F1: 10%, F2: 15% and F3: 20%. The physical stability test of the ethanol extract shampoo preparation of pondoh salak fruit peel (Salacca edulis Reinw) includes organoleptic test, homogeneity test, pH test, foam power test, viscosity test, free alkali test and storage stability test. Free alkali test results show that all formulations contain alkali. Storage stability test results for 6 cycles or 12 days at temperature 4OC and 40OC all dosage formulations remain stable. The results of the organoleptic test and homogeneity test remained stable, for the pH test and foam power there was a decrease and for the viscosity test there was an increase after the cycling test was carried out but it still met SNI requirements. Meanwhile, in testing the activity of Staphylococcus epidermidis in F1 10% the resulting inhibitory zone area was an average of 32.93 mm, in F2 15% the resulting inhibitory zone area was 28.56 mm, and in F3 20% the resulting inhibitory zone area was 20.93mm. Meanwhile, in the Candida albicans test, F1 10% inhibitory zone area averaged 24.61 mm, F2 15% average inhibitory zone area 25.94 mm, F3 inhibitory zone area 19.44 mm. Based on the results of the research that has been carried out, it can be concluded that the ethanol extract of pondoh salak fruit peel (Salacca edulis Reinw) meets the requirements of the physical stability test and can inhibit the growth of Staphylococcus epidermidis. The three inhibitory power measurements of each formulation are categorized as having a very strong inhibition zone area, while the activity testing for Candida Albicans F1 and F2 has a very strong zone of inhibition. very strong inhibition while F3 has a strong inhibition zone.

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Published
2024-02-16