Jurnal Kesehatan Yamasi Makassar
type: channel
description: Jurnal Kesehatan Yamasi merupakan jurnal resmi yang dipublikasikan oleh Akademi Farmasi Yamasi Makassar. Jurnal ini mencakup seluruh aspek ilmu farmasi sebagai berikut: farmasetika, kimia farmasi, biologi farmasi, bioteknologi farmasi, serta farmakologi dan farmasi klinik. Jurnal Kesehatan Yamasi terbit setiap 6 bulan yakni periode Januari dan Juli. Penerbitan jurnal ini didedikasikan untuk mempubikasikan hasil penelitian para dosen dan mahasiswa yang berkualitas.
publisher: Akademi Farmasi Yamasi Makassar
language: en
publication name: Jurnal Kesehatan Yamasi Makassar
issn: 2548-8279
items: EVALUASI PENYIMPANAN OBAT DAN ALAT KESEHATAN DI APOTEK REJEKI LESTARI
items: STUDI KOMPARASI ORGANOLEPTIK DAN STABILITAS FISIK SABUN CAIR BERBAHAN DASAR LIMBAH KULIT JERUK LEMON, NIPIS, DAN BALI
items: UJI AKTIVITAS EKSTRAK BIJI KOPI ROBUSTA (Coffea canephora) dan daun kersen (Muntingia calabura L.) TERHADAP PERTUMBUHAN BAKTERI Propionibacterium acnes
items: PENGARUH PERBEDAAN JENIS EMULGATOR PADA SEDIAAN LOTION EKSTRAK DAUN BIDARA (Ziziphus spina-christi L.) TERHADAP MUTU FISIK
items: UJI AKTIVITAS ANTIHIPERTENSI EKSTRAK DAUN AWAR-AWAR (Ficus septica Buirm F.) PADA TIKUS PUTIH (Rattus norvegicus)
items: FORMULASI DAN KARAKTERISASI SABUN ANTISEPTIK PADAT BERBASIS MINYAK JELANTAH DIPERKAYA EKSTRAK ETANOL DAUN BIDARA CINA (Ziziphus jujuba) UNTUK PEMANFAATAN BERKELANJUTAN
items: KARAKTERISASI EKSTRAK KULIT UBI JALAR UNGU (Ipomea batatas L Poir) BERDASARKAN BEBERAPA PARAMETER SPESIFIK EKSTRAK
items: Formulation and Production of Eco-Enzyme Herbal Bath Soap as a Natural Antiseptic
items: PEMBUATAN DAN UJI MUTU FISIK SEDIAAN DEODORAN SPRAY DARI EKSTRAK PELEPAH SEREH (Cymbopogon nardus L.)
items: TINJAUAN EFEK SAMPING PENGGUNAAN METFORMIN PADA PASIEN DIABETES MELITUS TIPE II DI APOTEK KIMIA FARMA ALAUDDIN BULAN JULI-DESEMBER 2023
items: Karakterisasi Mutu Fisik Teh Celup Kulit Buah Kopi Arabika (Coffea arabica L)
items: PEMBUATAN DAN UJI MUTU FISIK SEDIAAN SALEP KULIT DARI EKSTRAK BIJI KAKAO (Theobroma cacao L.)
items: UJI DAYA HAMBAT SEDIAAN TONER WAJAH INFUSA DAUN BELIMBING WULUH (Averrhoa bilimbi L.) TERHADAP Propionibacterium acnes
items: AKTIVITAS TABIR SURYA EKSTRAK ETANOL DAUN Acacia auriculiformis ASAL KOLAKA MENGGUNAKAN SPEKTROFOMETRI UV-Vis
items: ANALISIS FAKTOR RESIKO KEJADIAN TUBERCULOSIS DI WILAYAH PUSKESMAS SYAMTALIRA BAYU
items: UJI AKTIVITAS FRAKSI N-HEKSAN, ETIL ASETAT, ETANOL DAUN PARE (Momordica charantia L.) TERHADAP Staphylococcus epidermidis DAN Salmonella thypi
items: PEMBUATAN DAN UJI DAYA HAMBAT SEDIAAN SERUM WAJAH EKSTRAK DAUN PEPAYA (Carica papaya L.) TERHADAP staphylococcus epidermidis
items: UJI AKTIVITAS SABUN MANDI HERBAL ECOENZYME SEBAGAI ANTISEPTIK ALAMI TERHADAP Staphylococcus aureus DAN Propionibacterium acne
items: UJI EFEKTIVITAS GEL EKSTRAK DAUN MELINJO (Gnetum gnemon L.) TERHADAP Staphylococcus epidermidis
items: UJI DAYA HAMBAT EKSTRAK KULIT DAGING BUAH LONTAR (Borassus flabellifer L.) TERHADAP PERTUMBUHAN Staphylococcus aureus
items: DISTRIBUSI PENGGUNAAN BERAGAM JENIS VAKSIN COVID-19 DI WILAYAH KERJA PUSKESMAS GENTUNGAN, DESA GENTUNGAN, KECAMATAN BAJENG BARAT, KABUPATEN GOWA TAHUN 2022
items: PENGARUH PERBEDAAN KONSENTRASI EMULGATOR PADA SEDIAAN LOTION EKSTRAK DAUN BIDARA (Ziziphus spina-christi L.) TERHADAP MUTU FISIK
items: ANALISIS TINGKAT KEPUASAN PASIEN TERHADAP PELAYANAN KEFARMASIAN DI APOTEK TASIKMADU KARANGANYAR
items: PENGUJIAN AKTIVITAS SIRUP EKSTRAK BIJI DAN KULIT BUAH PEPAYA (Carica papaya L.) TERHADAP PERTUMBUHAN Escherichia coli
items: FORMULASI DAN UJI MUTU FISIK GRANUL EFFERVESCENT DARI TEMULAWAK (Curcuma xanthorrhiza Roxb)
items: PEMBUATAN DAN UJI MUTU FISIK SEDIAAN BODY LOTION PATI BENGKUANG (Pachyrhizus erosus L.).
items: POTENSI EKSTRAK ETANOL DAUN SUKUN (Artocarpus altilis) SEBAGAI BAHAN TABIR SURYA DENGAN PENENTUAN NILAI Sun Protection Factor (SPF) SECARA In Vitro
items: UJI EFEKTIVITAS EKSTRAK ETANOL BUAH BINTARO (Cerbera odollam Gaerthn) TERHADAP PENURUNAN GLUKOSA DARAH PADA TIKUS PUTIH (Rattus norvegicus)
items: EVALUASI MUTU FISIK DAN UJI IRITASI KOSMETIKA LULUR DENGAN MEMANFAATKAN BONGGOL NANAS SEBAGAI BAHAN AKTIF
items: PEMBUATAN DAN UJI MUTU FISIK SEDIAAN FACE MIST EKSTRAK DAUN ALPUKAT (Persea americana Mill.)

EVALUASI PENYIMPANAN OBAT DAN ALAT KESEHATAN DI APOTEK REJEKI LESTARI
type: item
description: The storage of medicines and medical devices is an important component in the implementation of pharmaceutical services, as it affects the quality, stability, safety, and therapeutic effectiveness of these products. Non-standard storage management may lead to active ingredient degradation, reduced quality of medical devices, and potential risks to patient safety. The implementation of an appropriate and regulation-based storage system plays a vital role in ensuring the quality of pharmaceutical services in healthcare facilities. The purpose of this study is to assess the compliance of drug and medical device storage at Apotek Rejeki Lestari with Technical Guidelines for the Implementation of Pharmaceutical Services issued by the Ministry of Health of the Republic of Indonesia at 2019. This study employed a descriptive observational method through direct observation. The measurement instrument used was a checklist consisting of 25 statements. Data collection was conducted in May 2025. The data were analyzed descriptively by calculating the percentage of storage compliance with the standards. The results showed that the overall storage aspects complied with the standards, with 21 indicators having been fulfilled. There were 4 indicators that did not meet the storage standards. The noncompliant aspects included the absence of an air conditioner to maintain room temperature and the lack of storage cabinets for High-Alert Medications (HAM), as well as for expired and damaged drugs. In conclusion, the storage system at Apotek Rejeki Lestari is very good, with a compliance rate of 84%; although improvements are needed in the aspect of high-risk medication.
subject: Articles
  topic: section
creator: Indria Purnama
creator: Anita Mursiany
creator: Hartono
creator: Retnowati Hartono
creator: Fitri Apriliany
rights: Copyright (c) 2026 Indria Purnama, anita mursiany, Hartono, Retnowati Hartono, Fitri Apriliany https://creativecommons.org/licenses/by/4.0
date: 2026-01-30
publication date: 2026-01-30
starting page: 80
ending page: 90
doi: 10.59060/4ck4zb88

STUDI KOMPARASI ORGANOLEPTIK DAN STABILITAS FISIK SABUN CAIR BERBAHAN DASAR LIMBAH KULIT JERUK LEMON, NIPIS, DAN BALI
type: item
description: This study aimed to compare the quality of liquid hand soap produced from lemon peel, lime peel, and pomelo peel as organic waste-based raw materials with antibacterial potential. The research applied an experimental approach with product development through the stages of defining, designing, developing, and disseminating. Citrus peels were extracted and formulated into liquid hand soap, then evaluated based on color, aroma, foam formation, acidity level, and antimicrobial activity against microbial growth using bread observation. Data were analyzed using descriptive qualitative analysis by comparing the characteristics of each soap variant. The results showed that lime peel soap produced a clear green color and strong aroma with neutral acidity, lemon peel soap generated the highest foam with a slightly alkaline acidity, while pomelo peel soap demonstrated the strongest ability to inhibit bacterial growth with stable physical characteristics. The findings indicate that different types of citrus peel significantly influence the physical and antimicrobial quality of liquid hand soap. The study also identified formulation stability issues related to oil separation and odor development, emphasizing the importance of filtration and preservation in natural soap production. This research highlights the potential of citrus peel waste as an environmentally friendly material for hygienic product innovation.
subject: Articles
  topic: section
creator: Dicky Agil Pamungkas
creator: Mentari Aulia Lintang Dinasty
creator: Aziizatun Nisa
creator: Viska Dilian Maimunah
creator: Azka Nabila Athaya
creator: Desi Wulandari
rights: Copyright (c) 2026 DICKY AGIL PAMUNGKAS, Mentari Aulia Lintang Dinasty, Aziizatun Nisa, Viska Dilian Maimunah, Azka Nabila Athaya, Desi Wulandari https://creativecommons.org/licenses/by/4.0
date: 2026-01-29
publication date: 2026-01-29
starting page: 65
ending page: 79
doi: 10.59060/mg6kdx12

UJI AKTIVITAS EKSTRAK BIJI KOPI ROBUSTA (Coffea canephora) dan daun kersen (Muntingia calabura L.) TERHADAP PERTUMBUHAN BAKTERI Propionibacterium acnes
type: item
description: This study aimed to evaluate the antibacterial activity of robusta coffee bean (Coffea canephora) and cherry leaf (Muntingia calabura L.) extracts against Propionibacterium acnes, as well as to identify their active phytochemical constituents and determine the most effective combination ratio. The research was conducted experimentally in a laboratory setting. Extraction was performed using the maceration technique with 96% ethanol as the solvent, followed by phytochemical screening for alkaloids, flavonoids, tannins, and saponins. The antibacterial activity was assessed using the disk diffusion method with various extract combination ratios of 25%:75%, 50%:50%, and 75%:25%. The inhibition zone diameters were statistically analyzed using a One- Way ANOVA test. The results revealed that both extracts contained secondary metabolites. The combination of robusta coffee bean and cherry leaf extracts at a 25%:75% ratio produced the largest inhibition zone (4.53 ± 1.71 mm), followed by 75%:25% (4.28 ± 2.51 mm) and 50%:50% (3.83 ± 1.24 mm). All were categorized as weak inhibition (<5 mm). Statistical analysis indicated that the data were normally distributed and homogeneous; however, no significant difference was observed among the treatment groups (p > 0.05).
subject: Articles
  topic: section
creator: Mira Bella Apriance
creator: Riza Dwiningrum
creator: Vicko Suswidiantoro
creator: Mida Pratiwi
rights: Copyright (c) 2026 Mira Bella Apriance, Riza Dwiningrum, Vicko Suswidiantoro, Mida Pratiwi https://creativecommons.org/licenses/by/4.0
date: 2026-01-29
publication date: 2026-01-29
starting page: 55
ending page: 64
doi: 10.59060/3fe6e905

PENGARUH PERBEDAAN JENIS EMULGATOR PADA SEDIAAN LOTION EKSTRAK DAUN BIDARA (Ziziphus spina-christi L.) TERHADAP MUTU FISIK
type: item
description: Bidara leaves contain phenolics and flavonoids which are effective as antioxidants. To increase the use value of bidara leaves, they are made into lotion preparations. This research aims to see the effect of different emulsifiers on lotion preparations from bidara leaf extract (Ziziphus spina-christi L.). Bidara leaves were extracted using a maceration method using 96% ethanol solvent for 3x24 hours. This lotion preparation was made with varying concentrations of Anionic and Nonionic emulsifiers and then carried out a physical evaluation including organoleptic tests, homogeneity tests, pH tests of the preparations, adhesion tests and spreadability tests. The results of the physical evaluation of lotion preparations with different types of emulsifiers influenced the pH of the bidara leaf extract lotion preparations, and in the organoleptic test, they were green and brown in color, had a distinctive aroma of bidara leaf extract, and had a soft texture. The lotion preparation is mixed homogeneously, has spreadability and stickiness values that meet the standard requirements.
subject: Articles
  topic: section
creator: Andi Nur Izzahtul Irwan
creator: Zulfahmi Hamka
rights: Copyright (c) 2026 Andi Nur Izzahtul Irwan, Zulfahmi Hamka https://creativecommons.org/licenses/by/4.0
date: 2026-01-29
publication date: 2026-01-29
starting page: 45
ending page: 54
doi: 10.59060/r7mxxp50

UJI AKTIVITAS ANTIHIPERTENSI EKSTRAK DAUN AWAR-AWAR (Ficus septica Buirm F.) PADA TIKUS PUTIH (Rattus norvegicus)
type: item
description: This study aims to determine the compound group and antihypertensive activity of the ethanol extract of awar awar leaves (Ficus septica Burm F.) based on the results of systolic and diastolic blood pressure measurements in Rattus norvegicus. The research design used an in-vivo laboratory experiment carried out in the pharmacology laboratory of the Faculty of Pharmacy, Muslim University of Indonesia. Awar-awar leaf simplicia was extracted by maceration with 70% ethanol solvent, the concentrated extract was calculated for its percent yield, and a phytochemical screening test was carried out. Fifteen male rats were divided into five groups, namely the negative control group (Na.CMC 1%), positive control (captopril), and the awar-awar leaf extract group with doses of 75 mg/kg BW, 150 mg/kg BW, and 300 mg/kg BW. Blood pressure was measured using a Non-Invasive (CODA) device. The results showed that the concentrated extract had a yield value of 3.24%. Positive phytochemical screening of alkaloid, flavonoid, tannin, saponin, phenolic, and terpenoid compounds. The average percentage of reduction in systolic and diastolic blood pressure of Rattus norvegicus in the negative control group (12.11/3.55%), positive control (41.97/22.77%), doses of 75 mg/kg BW (20.87/11.64%), 150 mg/kg BW (25.03/41.22%), and 300 mg/kg BW (38.14/45.83%) had antihypertensive activity that was not significantly different from captopril.
subject: Articles
  topic: section
creator: Sitti Fauziah Noer
creator: Mustainah
creator: Asriawalia
rights: Copyright (c) 2026 Sitti Fauziah Noer Sitti Fauziah Noer, Mustainah, Asriawalia https://creativecommons.org/licenses/by/4.0
date: 2026-01-29
publication date: 2026-01-29
starting page: 34
ending page: 44
doi: 10.59060/3jtw6e19

FORMULASI DAN KARAKTERISASI SABUN ANTISEPTIK PADAT BERBASIS MINYAK JELANTAH DIPERKAYA EKSTRAK ETANOL DAUN BIDARA CINA (Ziziphus jujuba) UNTUK PEMANFAATAN BERKELANJUTAN
type: item
description: Used cooking oil is a household waste that has the potential to pollute the environment, while Chinese bidara leaves (Ziziphus jujuba) are known to have a variety of biological activities, including antibacterial. Utilizing these two components in solid antiseptic soap formulations can provide added value and sustainable solutions. Objective: This study aims to formulate a solid antiseptic soap preparation based on used cooking oil with the addition of ethanol extract of Chinese bidara leaves that meets SNI quality requirements, and evaluate its physical, chemical, and antibacterial activity characteristics. Methods: Used cooking oil was purified with coconut fiber charcoal. Chinese bidara leaf ethanol extract was added to the soap at 5% (F1) and 10% (F2) concentrations, compared to the blank (F0). Tests include organoleptic (shape, color, aroma), pH, foam height, water content, free fatty acids, and free alkali. Antibacterial activity was tested against Staphylococcus aureus, Staphylococcus epidermidis, and Propionibacterium acne. Results: All soap formulas showed good organoleptic characteristics (solid, distinctive aroma) with color variations according to extract concentration. The pH value (9.7-10.1) and foam height (59.67-75.33 mm) met SNI. Water content (8.3- 9.31%) and free fatty acids (2.0-2.3%) also met the standard. However, the free alkali content of Formula 2 (0.2%) exceeded the SNI limit (<0.1%). All formulas with extracts showed zones of inhibition against the three test bacteria, and the zones of inhibition increased with the concentration of the extracts.
subject: Articles
  topic: section
creator: Zakiah Thahir
creator: Yuyun Sri Wahyuni
creator: Hernawati Basir
creator: Istianah Purnamasari
creator: Adrival Darwin
creator: Aisyah
creator: Indah Lestari
rights: Copyright (c) 2026 Zakiah Thahir, Yuyun Sri Wahyuni, Hernawati Basir, Istianah Purnamasari, Adrival Darwin, Aisyah, Indah Lestari https://creativecommons.org/licenses/by/4.0
date: 2026-01-29
publication date: 2026-01-29
starting page: 19
ending page: 33
doi: 10.59060/aap2gh31

KARAKTERISASI EKSTRAK KULIT UBI JALAR UNGU (Ipomea batatas L Poir) BERDASARKAN BEBERAPA PARAMETER SPESIFIK EKSTRAK
type: item
description: Anthocyanin is a secondary metabolite of plants that can be used as a natural dye. Purple sweet potato (Ipomea batatas L Poir) is a food ingredient known to contain high anthocyanin compared to other types of sweet potatoes. Purple sweet potato skin which is usually not used can be used as an alternative to obtain anthocyanin as a natural dye. This study aims to determine the characteristics of purple sweet potato skin extract including extract soaking, water content, watersoluble extract content, ethanol-soluble extract content as standard parameters of extract quality. The study showed that the sweet potato skin extract produced was a thick extract, dark purple in color, slightly sweet in taste and distinctive odor, extract soaking value of 7.86% water content 15.28%, watersoluble extract content 32.82% and ethanol-soluble extract content 18.06%.
subject: Articles
  topic: section
creator: Nurul Hidayah Base
creator: Raymond Arief N Noena
creator: Adnan Ahmad
rights: Copyright (c) 2026 Nurul Hidayah Base, Raymond Arief N Noena, Adnan Ahmad https://creativecommons.org/licenses/by/4.0
date: 2026-01-29
publication date: 2026-01-29
starting page: 10
ending page: 18
doi: 10.59060/183x3j29

Formulation and Production of Eco-Enzyme Herbal Bath Soap as a Natural Antiseptic
type: item
description: This study aimed to develop herbal bath soap formulations based on eco enzyme and evaluate their physical characteristics according to SNI quality standards. The soap was formulated using the Cold Process method with three formula variations: F0, F1, and F2. The pH test results showed that all formulas were within the range of 9.03–9.05, meeting the SNI standard. The moisture content test showed the lowest value in F0 and the highest in F2, all of which were within the SNI standard. The total fat of the formulas ranged from 45.005% to 52.815%, meeting the maximum limit of the SNI. The free alkali values of all formulas ranged from 0.0095% to 0.0949%, in accordance with the SNI standard. Formula F2 was considered the best formulation because it produced soap with optimal physical characteristics and met all standard parameters. Eco enzyme has been proven effective as an active ingredient with potential antifungal, antibacterial, and natural cleansing properties in herbal bath soap formulations.
subject: Articles
  topic: section
creator: Muhammad Tahir
rights: Copyright (c) 2025 Muhammad Tahir
date: 2025-01-30
publication date: 2025-01-30
starting page: 26
ending page: 31
doi: 10.59060/jurkes.v9i1.373

PEMBUATAN DAN UJI MUTU FISIK SEDIAAN DEODORAN SPRAY DARI EKSTRAK PELEPAH SEREH (Cymbopogon nardus L.)
type: item
description: This study aims to determine the preparation and physical quality test of deodorant spray preparation from lemongrass frond extract (Cymbopogon nardus L.) The research method used is laboratory experimental. First the simplisia was extracted by maceration method for 2 x 24 hours using 96% ethanol solvent. The results of the thick extract were made deodorant spray preparations in the form of 4 formulas F1 27%, F2 28% and F3 29% with a deodorant spray base consisting of 96% ethanol, propylenglicol and distilled water. Physical quality tests carried out are organoleptic test, pH test, homogeneity test and dry time test. The results of the organoleptic test F0, F1, F2, F3 have a liquid form, distinctive odor and orange color while for F0 has a liquid form, odorless and clear color. The results of the pH test F0, F1, F2, F3 all preparations have met the requirements with a pH parameter value of 3 - 7.5. The homogeneity test results of all preparations have met the requirements. The dry time test has met the requirements with a drying time of < 5 minutes in the deodorant spray preparation. From the results of the study stated that lemongrass frond extract (Cymbopogon nardus L.) can be made in the form of deodorant spray preparations with a concentration of F0 base, F1 27%, F2 28%, F3 29% have met the quality requirements based on SNI 16-4951-1998.
subject: Articles
  topic: section
creator: Agust Dwi Djajanti Djajanti
rights: Copyright (c) 2025 Agust Dwi Djajanti Djajanti
date: 2025-02-05
publication date: 2025-02-05
starting page: 41
ending page: 47
doi: 10.59060/jurkes.v9i1.368

TINJAUAN EFEK SAMPING PENGGUNAAN METFORMIN PADA PASIEN DIABETES MELITUS TIPE II DI APOTEK KIMIA FARMA ALAUDDIN BULAN JULI-DESEMBER 2023
type: item
description: Diabetes Melitus tipe II adalah penyakit dengan suatu kondisi yang mempengaruhi cara tubuh memproses gula darah. Pengobatan lini pertama penderita DM tipe II menggunakan metformin. Namun disamping itu, metformin dapat menimbulkan beberapa efek samping yang tidak diinginkan. Tujuan penelitian ini adalah untuk mengetahui efek samping dari penggunaan Metformin pada penderita DM tipe II. Jenis penelitian yang digunakan bersifat deskriptif yang pengumpulan datanya secara retrospektif. Berdasarkan hasil penelitian yang telah dilakukan dapat diketahui penderita DM tipe II yang paling banyak mengalami efek samping di Apotek Kimia Farma Alauddin Makassar yakni pada usia 60 tahun ke atasdengan efek samping terbanyak adalah defisiensi vit. B12 dengan persentase 10,88%. Berdasarkan dosis obat harian penggunaan metformin diketahui banyak dikonsumsi yang menimbulkan efek samping yakni 2 x 500 mg (48%).
subject: Articles
  topic: section
creator: sukirawati sukirawati
rights: Copyright (c) 2025 sukirawati sukirawati
date: 2025-02-05
publication date: 2025-02-05
starting page: 48
ending page: 55
doi: 10.59060/jurkes.v9i1.375

Karakterisasi Mutu Fisik Teh Celup Kulit Buah Kopi Arabika (Coffea arabica L)
type: item
description: Kulit buah kopi arabika (Coffea arabica L.) merupakan bagian terluar dari buah kopi yang mengandung senyawa polifenol yang dapat menangkal radikal bebas dan memiliki aktivitas antioksidan yang tinggi, namun belum dimanfaatkan secara maksimal oleh masyarakat. Penelitian ini bertujuan untuk mengetahui apakah kulit buah kopi arabika dapat dibuat dalam sediaan teh celup herbal dan mengetahui karakterisasi mutu fisiknya berdasarkan keadaan air seduhan, pH, kadar air dan kadar ekstrak dalam air. Metode penelitian yang digunakan adalah eksperimental laboratorium dengan melakukan pembuatan teh celup herbal kulit buah kopi arabika yang selanjutnya dilakukan karaketrisasi mutu fisik dengan mengacu pada SNI (3836 : 2013). Hasil pengujian karakteristik mutu fisik teh celup herbal kulit buah kopi arabika menunjukkan bahwa keadaan air seduhan berwarna merah kecoklatan, berbau khas aromatik dan tidak berasa. pH sebesar 4 (persyaratan pH 3,7-6,1), kadar air sebesar 7,7 % (< 8%), dan kadar ekstrak dalam air sebesar 36 % (> 32 %). Sehingga dapat disimpulkan bahwa kulit buah kopi arabika dapat dibuat menjadi teh celup herbal dengan karakterisasi mutu fisik yang sesuai dengan syarat mutu fisik teh kering dalam kemasan.
subject: Articles
  topic: section
creator: Nurul Hidayah Base
rights: Copyright (c) 2025 Nurul Hidayah Base
date: 2025-02-05
publication date: 2025-02-05
starting page: 56
ending page: 65
doi: 10.59060/jurkes.v9i1.376

PEMBUATAN DAN UJI MUTU FISIK SEDIAAN SALEP KULIT DARI EKSTRAK BIJI KAKAO (Theobroma cacao L.)
type: item
description: Abstract. This research aims to make a preparation of cocoa bean extract (Theobroma cacao L.) skin ointment that meets the requirements for a good physical quality test for skin ointment using vaseline album and adeps lanae ointment bases. Cocoa beans (Theobroma cacao L.) were extracted using the maceration method using 96% ethanol then the extraction results were made into 3 skin ointment preparations with the same base and using cocoa bean extract (Theobroma cacao L.) with a concentration of 5% b/b, 10 % b/b, and 15% b/b. The research results show that skin ointment preparations with extract concentrations of 5% b/b, 10% b/b, and 15% b/b can meet the physical quality test parameters including organoletic tests which produce a semi-solid form, distinctive odor, brown color, test homogeneity obtained homogeneous results, the pH test obtained a pH of 5 which met the skin pH requirements of 4.5 – 6.5, the spreadability test obtained results for a concentration of 5% b/b resulting in a spreadability of 5.2 cm, a concentration of 10% b/b b produced 5.6 cm, and a concentration of 15% b/b produced 6.5 cm, where this result met the standard requirements for good ointment spreadability in the range of 5 - 7 cm, and the adhesive test produced 20 - 37 seconds. Where this result meets the adhesion requirement, namely more than 4 seconds.
subject: Articles
  topic: section
creator: Rusmin Rusmin
rights: Copyright (c) 2025 Rusmin Rusmin
date: 2025-02-05
publication date: 2025-02-05
starting page: 32
ending page: 40
doi: 10.59060/jurkes.v9i1.366

UJI DAYA HAMBAT SEDIAAN TONER WAJAH INFUSA DAUN BELIMBING WULUH (Averrhoa bilimbi L.) TERHADAP Propionibacterium acnes
type: item
description: . This research has been made with the objective to determine at what concentration the infusa of bilimbi leaves (Averrhoa bilimbi L.) in the form of facial toner preparations can inhibit Propionibacterium acnes bacteria optimally. The method used in this research is a laboratory experimental method by testing the inhibition of toner preparations. Belimbing wuluh leaves were extracted using the infusa method then made facial toner preparations with concentrations of 10%, 20% and 30% and tested with the paperdisk method. From the results of the research on the inhibition of facial toner preparations of infusa extract of bilimbi leaves (Averrhoa bilimbi L.) showed that at concentrations of 10% and 20% could not inhibit the growth of Propionibacterium acnes bacteria. Meanwhile, the 30% concentration can inhibit the growth of Propionibacterium acnes bacteria optimally optimally with the inhibition zone around the paperdisk.
subject: Articles
  topic: section
creator: yusriyani burhamin
rights: Copyright (c) 2025 yusriyani burhamin
date: 2025-02-06
publication date: 2025-02-06
starting page: 66
ending page: 73
doi: 10.59060/jurkes.v9i1.374

AKTIVITAS TABIR SURYA EKSTRAK ETANOL DAUN Acacia auriculiformis ASAL KOLAKA MENGGUNAKAN SPEKTROFOMETRI UV-Vis
type: item
description: Excessive exposure to UV radiation can cause skin damage. Preventive measures can be taken by using sunscreen. Acacia auriculiformis is a species from the Fabaceae family, many of which are known for their antioxidant activity. Acacia auriculiformis can act as a natural sunscreen because it contains secondary metabolite compounds with conjugated double bond structures, which are known to reduce the intensity of UV exposure on the skin by absorbing ultraviolet radiation. This study aimed to identify the secondary metabolites in the ethanol extract of Acacia auriculiformis leaves from Kolaka and to determine its Sun Protection Factor (SPF) value using UV-Vis spectrophotometry. The extraction of Acacia auriculiformis leaves was carried out using the maceration method with 70% ethanol as the solvent. The sunscreen activity was determined based on the SPF values. The SPF values of the extract at concentrations of 50 ppm, 100 ppm, 150 ppm, and 200 ppm were 3.8712 (minimal protection), 6.4880 (extra protection), 9.5359 (maximum protection), and 12.5816 (maximum protection), respectively. The results indicate that sunscreen activity increases in proportion to the extract concentration. Acacia auriculiformis leaves have the potential to be developed as a sunscreen formulation.
subject: Articles
  topic: section
creator: Andri Anugrah Pratama
creator: Akhmad Ardiansyah
creator: Muhammad Taufik Duppa
creator: Anshari Masri
rights: Copyright (c) 2025 Andri Anugrah Pratama
date: 2025-07-28
publication date: 2025-07-28
starting page: 17
ending page: 25
doi: 10.59060/jurkes.v9i2.401

ANALISIS FAKTOR RESIKO KEJADIAN TUBERCULOSIS DI WILAYAH PUSKESMAS SYAMTALIRA BAYU
type: item
description: World Health Organization (WHO) menyatakan Tuberkullosis (TB) sebagai masalah kesehatan masyarakat yang sangat penting dan serius diseluruh dunia dan merupakan penyakit yang menimbulkan kedaruratan global (Global Emergency) karena di sebagian besar negara di dunia penyakit TB paru tidak terkendali, Hal ini disebabkan oleh banyaknya penderita yang tidak berhasil disembuhkan, serta merupakan penyebab utama kematian yang disebabkan oleh penyakit infeksi Penelitian ini merupakan penelitian kasus kontrol yang bertujuan untuk menganalisis hubungan antara diabetes melitus (DM) dengan kejadian tuberkulosis (TB) pada seluruh pasien TB di wilayah kerja Puskesmas Syamtalira Bayu. Variabel data mengenai riwayat penyakit DM, usia, jenis kelamin, pekerjaan, kontak dengan pasien TB dan riwayat vaksin BCGA. Analisis data pada Tabel 1 menunjukkan profil pasien TB paru yang didominasi oleh lansia dengan usia di atas 49 tahun (63,16%) dan perempuan (73,68%). Pekerjaan sebagai ibu rumah tangga merupakan pekerjaan yang paling banyak dilakukan oleh responden (8 orang), diikuti oleh pelajar/mahasiswa, wiraswasta, dan tidak bekerja. Kondisi komorbiditas diabetes melitus juga cukup signifikan, dengan 63,16% responden memiliki riwayat penyakit ini. Menariknya, meskipun TB sering dikaitkan dengan kontak langsung dengan pasien, mayoritas responden (73,68%) tidak memiliki riwayat kontak langsung dengan pasien TB sebelumnya. Selain itu, semua responden tidak memiliki riwayat vaksinasi BCG. Kesimpulan dari laporan ini menunjukkan bahwa tuberkulosis (TB) masih menjadi masalah kesehatan yang signifikan, terutama di kalangan lansia yang memiliki faktor risiko seperti diabetes melitus (DM). Penelitian ini mengungkapkan bahwa individu berusia di atas 49 tahun dengan DM memiliki kemungkinan yang lebih tinggi untuk mengalami kejadian TB.
subject: Articles
  topic: section
creator: Ambia Nurdin
creator: Nabila Dwi Putri
creator: Ulfa Nazillah
creator: Hariska Azhari
creator: Aypa Safitri
creator: Sadri Lafiska
creator: Ulvi Maghvira
creator: Dewi Astini
rights: Copyright (c) 2025 Ambia Nurdin, Nabila Dwi Putri, Ulfa Nazillah, Hariska Azhari, Aypa Safitri, Sadri Lafiska, Ulvi Maghvira, Dewi Astini
date: 2025-07-28
publication date: 2025-07-28
starting page: 1
ending page: 9
doi: 10.59060/jurkes.v9i2.383

UJI AKTIVITAS FRAKSI N-HEKSAN, ETIL ASETAT, ETANOL DAUN PARE (Momordica charantia L.) TERHADAP Staphylococcus epidermidis DAN Salmonella thypi
type: item
description: Bitter melon leaves (Momordica charantia L.) contain compounds such as flavonoids, saponins, triterpenoids, glycosides and alkaloids. This study aims to determine the difference in antibacterial activity of the N-hexane, Ethyl acetate and Ethanol 96% fractions fram bitter melon leaves (Momordica charantia L.) against the bacteria Staphylococcus epidermidis and Salmonella thypi. The research method is an experimental study to see the antibacterial activity of the N-hexane, ethyl acetate and etanol 96% fractions at concentrations of 5%, 10% and 15% using the disc diffusion method. The results of the research showed that Staphylococcus epidermidis bacteria obtained an inhibitory power of 5% (5,95 mm), 10% (12,23 mm), 15% (14,05 mm) for the N-hexane fraction. Ethyl acetate fraction 5% (6,08 mm), 10% (7,37 mm), 15% (10,93 mm). Ethanol fraction of 5% (6,37 mm), 10% (12,8 mm), 15% (13,98 mm). Salmonella thypi bacteria against the N-hexane fraction obtained an inhibitory power of 5% (7,83 mm), 10% (12,47 mm), 15% (13,88 mm). The ethyl acetate fraction is 5% (5,43 mm), 10% (10,85 mm), 15% (13,88 mm). Ethanol fraction of 5% (7,77 mm), 10% (10,27 mm), 15% (15,5 mm). It can be concluded that the N-hexane, ethyl acetate and ethanol 96% fractions have antibacterial activity.
subject: Articles
  topic: section
creator: Muhammad Asri SR
creator: Rezky Amaliah Kasim
creator: Suryanita
rights: Copyright (c) 2025 Rezky Amaliah Kasim
date: 2025-07-28
publication date: 2025-07-28
starting page: 10
ending page: 16
doi: 10.59060/jurkes.v9i2.380

PEMBUATAN DAN UJI DAYA HAMBAT SEDIAAN SERUM WAJAH EKSTRAK DAUN PEPAYA (Carica papaya L.) TERHADAP staphylococcus epidermidis
type: item
description: This study aims to determine the inhibitory power of facial serum preparations from papaya leaf extract (Carica papaya L.) on the growth of Staphylococcus epidermidis. The research method carried out was experimental laboratory research, to determine the inhibitory power of facial serum from papaya leaf extract (Carica papaya L.) on the growth of Staphylococcus epidermidis which was carried out at the Microbiology Laboratory of the Yamasi Pharmacy Academy, Makassar. Papaya leaves were extracted using the maceration method using 96% ethanol solvent, the extract obtained was then made into a facial serum preparation with a concentration of 6% (F1), 8% (F2), 10% (F3) and as a serum base (F4). The research results stated that facial serum preparations of papaya leaf extract (Carica papaya L.) could inhibit the growth of Staphylococcus epidermidis with concentrations of 6%, 8%, and 10%.
subject: Articles
  topic: section
creator: Ananda Ramadani
creator: Rr. Widya Nurul Khatima
creator: Friskila Bernadeta Erare
rights: Copyright (c) 2025 ananda ramadani
date: 2025-07-30
publication date: 2025-07-30
starting page: 26
ending page: 34
doi: 10.59060/jurkes.v9i2.353

UJI AKTIVITAS SABUN MANDI HERBAL ECOENZYME SEBAGAI ANTISEPTIK ALAMI TERHADAP Staphylococcus aureus DAN Propionibacterium acne
type: item
description: Evaluation of the Antiseptic Activity of Herbal Bath Soap Containing Eco Enzyme Against Staphylococcus aureus and Propionibacterium acnes. Herbal bath soap is a skin cleanser formulated with a soap base and permitted additives to enhance its functionality and consumer appeal. The use of natural ingredients, particularly fruit and vegetable waste, offers a sustainable source of active compounds. Through fermentation, these materials can be converted into eco enzyme, which contains various bioactive substances with potential antibacterial properties. This study aimed to assess the antibacterial activity of herbal bath soap formulated with eco enzyme against Staphylococcus aureus and Propionibacterium acnes. The inhibition zone assay demonstrated that soap containing 25% and 50% eco enzyme exhibited average inhibition zones of 1.596 mm and 1.69 mm against P. acnes, respectively, while the negative control produced a zone of 0.88 mm. For S. aureus, the inhibition zones at the same concentrations were 3.44 mm and 1.997 mm. These findings suggest that eco enzyme-based herbal bath soap exhibits antibacterial effects against both tested bacterial strains. However, the observed inhibition remains within the weak category (<5 mm), indicating a limited but measurable antibacterial potential.
subject: Articles
  topic: section
creator: Muhammad Tahir
rights: Copyright (c) 2025 Muhammad Tahir
date: 2025-07-30
publication date: 2025-07-30
starting page: 35
ending page: 42
doi: 10.59060/jurkes.v9i2.393

UJI EFEKTIVITAS GEL EKSTRAK DAUN MELINJO (Gnetum gnemon L.) TERHADAP Staphylococcus epidermidis
type: item
description: Penelitian ini bertujuan Untuk mengetahui efektivitas sediaan gel ekstrak daun melinjo (Gnetum gnemon L.) dalam menghambat pertumbuhan bakteri Staphylococcus epidermidis dan konsentrasi optimum sediaan gel ekstrak daun melinjo dalam menghambat pertumbuhan Staphylococcus epidermidis. Daun melinjo diekstraksi menggunakan metode maserasi dengan etanol 96% dan diformulasikan menjadi sediaan gel konsentrasi 1%, 2%, dan 3%. Uji aktivitas antibakteri dilakukan dengan metode paperdisk pada media Nutrient Agar (NA) yang telah diinokulasi bakteri uji, serta menggunakan klindamisin sebagai kontrol positif dan basis gel sebagai kontrol negatif. Hasil menunjukkan bahwa gel ekstrak daun melinjo efektif dalam menghambat pertumbuhan Staphylococcus epidermidis. Dan konsentrasi optimum dari gel ekstrak daun melinjo yang dapat menghambat pertumbuhan Staphylococcus epidermidis adalah konsentrasi 3% dengan rata-rata diameter zona hambat 14,43 mm dengan kategori kuat.
subject: Articles
  topic: section
creator: Dzulasfi
creator: Nur Fajrina
rights: Copyright (c) 2025 dzulasfi
date: 2025-07-30
publication date: 2025-07-30
starting page: 43
ending page: 49
doi: 10.59060/jurkes.v9i2.399

UJI DAYA HAMBAT EKSTRAK KULIT DAGING BUAH LONTAR (Borassus flabellifer L.) TERHADAP PERTUMBUHAN Staphylococcus aureus
type: item
description: Kulit daging buah lontar (Borassus flabellifer L) memiliki banyak kandungan Flavonoid, tanin, dan saponin yang merupakan kandungan kimia yang berkhasiat sebagai pengobatan. Penelitian ini bertujuan untuk mengetahui aktivitas ekstrak kulit daging buah lontar (Borassus flabellifer L.) terhadap Staphyloccous aureus dan menentukan konsentrasi optimal ekstrak kulit daging buah lontar Staphylococcus aureus. kulit daging buah lontar (Borassus flabellifer L.) Dibuat dalam sediaan ekstrak dengan konsentrasi 5%, 10%, 15% pengujian ini menggunakan metode eksperimental kemudian dilakukan pengujian daya hambat ekstrak kulit daging buah lontar (Borassus flabellifer L.) dengan menggunakan variasi konsentrasi 5%, 10%, 15% serta kontrol negatif menggunakan DMSO menggunakan metode paper disk dan medium agar ( NA) sebagai media dan di inkubasi selama 1 x 24 jam. Hasil penelitian menunjukkan bahwa ekstrak kulit daging buah lontar (Borassus flabellifer L.) memiliki daya hambat terhadap pertumbuhan bakteri Staphylococcus aureus. Ekstrak yang digunakan dalam tiga konsentrasi, yaitu 5%, 10%, dan 15%, menunjukkan total diameter zona hambat masing-masing sebesar 44,6 mm, 45,3 mm, dan 52 mm, dengan rata-rata zona hambat sebesar 14,8 mm, 15,1 mm, dan 17,3 mm. Seluruh hasil tersebut termasuk dalam kategori daya hambat kuat.
subject: Articles
  topic: section
creator: Arief Azis
creator: Ismail
rights: Copyright (c) 2025 Arief Azis
date: 2025-07-30
publication date: 2025-07-30
starting page: 50
ending page: 57
doi: 10.59060/jurkes.v9i2.395

DISTRIBUSI PENGGUNAAN BERAGAM JENIS VAKSIN COVID-19 DI WILAYAH KERJA PUSKESMAS GENTUNGAN, DESA GENTUNGAN, KECAMATAN BAJENG BARAT, KABUPATEN GOWA TAHUN 2022
type: item
description: In December 2019, Wuhan City in Hubei Province, China, became the epicenter of a novel coronavirus outbreak, later identified as SARS-CoV-2, the causative agent of COVID-19. Common symptoms of COVID-19 infection include fever, cough, and shortness of breath. This study aimed to determine the percentage distribution of various COVID-19 vaccine types administered at the Gentungan Public Health Center. Employing a non-experimental, descriptive approach, this research analyzed existing data without intervention on test subjects, utilizing a retrospective data collection method. The study population comprised 9,000 individuals, from which a sample of 383 participants was selected. The results indicated the following distribution of vaccine usage: Sinovac was administered to 236 individuals (61.61%), Pfizer to 61 individuals (15.92%), Moderna to 53 individuals (13.83%), and AstraZeneca to 33 individuals (8.61%). Sinovac was the most frequently administered vaccine, likely due to its ample availability and the lack of choice afforded to the public regarding vaccine selection.
subject: Articles
  topic: section
creator: Hernawati Basir
creator: Istiana Purnamasari
creator: Yuyun Sri Wahyuni
creator: Delvi SJP
creator: A Tenriugi Daeng Pine
rights: Copyright (c) 2025 A Tenriugi Daeng Pine
date: 2025-07-30
publication date: 2025-07-30
starting page: 58
ending page: 65
doi: 10.59060/jurkes.v9i2.396

PENGARUH PERBEDAAN KONSENTRASI EMULGATOR PADA SEDIAAN LOTION EKSTRAK DAUN BIDARA (Ziziphus spina-christi L.) TERHADAP MUTU FISIK
type: item
description: Bidara leaves contain many useful ingredients, including alkaloids, phenols, flavonoids, saponins, quercetin, and terpenoids and the leaves have the potential to act as natural antioxidants.To increase the utilization or use value of bidara leaves they can be mae into a preparation, namely lotion. The aim of this research is to make and test the quality of a physicalpreparation of lotion from bidara leaf extract (Ziziphus spina-christi L.). Bidara leaves were extracted using a maceration method using 96% ethanol solvent for 3x24 hours. This lotion preparation is made with varying concentrations of Anionic and Nonionic emulsifiers and then a physical evaluation is carried out including organoleptic tests, homogeneity tests, pH tests of the preparations, adhesion tests and spreadability tests. Based on the results of the research carried out, it can be concluded that differences in emulsifier concentration affect quality including organoleptics, adhesion, dispersion and pH. The results of the physical evaluation of lotion preparations in the organoleptic test were that F1 was brown, F2 was green, had a distinctive aroma, F1 preparation was thick, F2 was slightly thick and both textures were smooth. The lotion preparation was mixed homogeneously, the pH and adhesion tests met the standard requirements but the spreadability test did not meet the standard requirements.
subject: Articles
  topic: section
creator: Zulfahmi Hamka
creator: Nurul Ilmi Muis
rights: Copyright (c) 2025 Zulfahmi Hamka
date: 2025-07-30
publication date: 2025-07-30
starting page: 66
ending page: 77
doi: 10.59060/jurkes.v9i2.382

ANALISIS TINGKAT KEPUASAN PASIEN TERHADAP PELAYANAN KEFARMASIAN DI APOTEK TASIKMADU KARANGANYAR
type: item
description: Patient satisfaction is an important and crucial indicator of service quality and pharmacy performance. Therefore, pharmacies must be oriented towards patient satisfaction and patient safety in every service provided. Continuous improvement needs to be done in order to maintain service quality. Periodic and continuous evaluation is a must carried out by pharmacies. The purpose of this study was to determine the performance of pharmacies in their pharmaceutical services to patients. This research design is descriptive quantitative with observational methods through prospective studies. The population and sample were customers who had experienced the services of Tasikmadu Pharmacy from February - March 2025 by giving questionnaires to 100 patients of Tasikmadu Pharmacy. Measurement of satisfaction based on servqual dimensions, namely assurance, empathy, responsiveness, physical facilities (tangible), and reliability. Data analysis using Likert scale. Based on the results of the analysis, the level of satisfaction with services in the guarantee dimension at Tasikmadu Pharmacy is very satisfied with a score of 90.91%, the empathy dimension is very satisfied (90.5%), the responsiveness dimension (89.5%), the physical facilities dimension (88.43%), and the reliability dimension (87.17%). The achievement of a satisfaction score of 89.30% in the five dimensions of service indicates that the services at the Tasikmadu Pharmacy are considered very satisfying by patients. However, it is necessary for pharmacies to continue to strive to improve their performance in providing services to patients, especially in the reliability dimension.
subject: Articles
  topic: section
creator: Anisa
creator: Hartono
creator: Retnowati Adiningsih
rights: Copyright (c) 2025 Retnowati Adiningsih, Hartono
date: 2025-07-31
publication date: 2025-07-31
starting page: 78
ending page: 89
doi: 10.59060/jurkes.v9i2.389

PENGUJIAN AKTIVITAS SIRUP EKSTRAK BIJI DAN KULIT BUAH PEPAYA (Carica papaya L.) TERHADAP PERTUMBUHAN Escherichia coli
type: item
description: This study aims to determine the antibacterial activity and the inhibition zone category of papaya (Carica papaya L.) seed and peel extract syrup against the growth of Escherichia coli. Papaya seed and peel extracts were formulated into syrup preparations with concentrations of 5% and 15%. Testing was carried out experimentally at the Microbiology Laboratory of the Yamasi Makassar Pharmacy Academy using the paper disk method on Nutrient Agar (NA) media, then incubated for 24 hours at 37°C. The measurement results showed that the inhibition zone in papaya seed extract syrup was 8.9 mm at a concentration of 5% and 10.28 mm at a concentration of 15%, which was categorized as moderate (6–10 mm). Meanwhile, papaya peel extract syrup produced an inhibition zone of 11.65 mm at a concentration of 5% and 13.45 mm at a concentration of 15%, classified as strong (11–20 mm). In conclusion, papaya seed and peel extract syrup with a concentration of 15% has a higher effectiveness in inhibiting the growth of Escherichia coli compared to a concentration of 5%.
subject: Articles
  topic: section
creator: Agust Dwi Djajanti Djajanti
creator: Putri Naila
rights: Copyright (c) 2025 Agust Dwi Djajanti Djajanti
date: 2025-07-31
publication date: 2025-07-31
starting page: 104
ending page: 113
doi: 10.59060/jurkes.v9i2.388

FORMULASI DAN UJI MUTU FISIK GRANUL EFFERVESCENT DARI TEMULAWAK (Curcuma xanthorrhiza Roxb)
type: item
description: Abstract. Curcuma (Curcuma xanthorrhiza Roxb) is a leading Indonesian medicinal plant that needs to be developed and utilized. Temu buffoonery contains various chemical compounds, starch is one of the most abundant ingredients found in the temu buffoonery plant. This research aims to formulate Curcuma (Curcuma xantoriza Roxb) rhizome, citric acid, tartaric acid, sodium bicarbonate, lactose, 70% alcohol and to test the physical quality of the preparation which includes organoleptic test, flow time test, soluble time test, water content test. , and the pH test resulted that the effervescent granule preparation met the physical quality requirements as a good effervescent preparation. Based on the research results, the best formula concentration data was obtained in each physical quality test of the preparation, namely formula III with a binder concentration of 6% (P <0.05), with an average flow time (9.20 seconds), dissolution time (3.46 minutes) , moisture content (0.54%), pH (6.86). This reaffirms that the research has successfully developed a granular effervescent formulation from Curcuma (Curcuma xanthorrhiza Roxb) that meets physical quality standards, especially in Formula III with a 6% binding concentration. This achievement opens up opportunities for a broader utilization of traditional Indonesian medicinal plants in a more modern and effective form. Furthermore, this finding also emphasizes the need for further research, which can focus on exploring the bioactive potential of Curcuma and further formulation innovation.
subject: Articles
  topic: section
creator: Rusmin
rights: Copyright (c) 2025 Rusmin Rusmin
date: 2025-07-31
publication date: 2025-07-31
starting page: 114
ending page: 122
doi: 10.59060/jurkes.v9i2.392

PEMBUATAN DAN UJI MUTU FISIK SEDIAAN BODY LOTION PATI BENGKUANG (Pachyrhizus erosus L.).
type: item
description: Body lotion is a skin moisturizing cosmetic that is included in the emollient (softener) group, has moisturizing properties and is easy to apply to the skin. Body lotion can be made from plants, one of which is yam tubers. A study has been conducted with the aim of making and testing the physical quality of yam starch body lotion preparations (Pachyrhizus erosus L.). This research method was carried out using experimental research, namely making body lotion preparations from yam starch (Pachyrhizus erosus L.). Body lotion preparations from yam starch (Pachyrhizus erosus L.) were made with variations in concentration F0 (base), F1 3%, F2 5%, F3 7%. Evaluation of body lotion preparations includes organoleptic tests, homogeneity tests, pH tests, and spreadability tests. The results of the study showed that yam starch can be made into body lotion preparations that meet physical quality including organoleptic tests, namely white in color, distinctive aroma, slightly thick in shape and soft in texture. The body lotion preparation was mixed homogeneously and had an average pH value of 6, and an average spread of 6.4 cm.
subject: Articles
  topic: section
creator: Taufiq
creator: Andi Idrus Andriawan
rights: Copyright (c) 2025 taufiq taufiq https://creativecommons.org/licenses/by/4.0
date: 2025-08-13
publication date: 2025-08-13
starting page: 123
ending page: 131
doi: 10.59060/jurkes.v9i2.387

POTENSI EKSTRAK ETANOL DAUN SUKUN (Artocarpus altilis) SEBAGAI BAHAN TABIR SURYA DENGAN PENENTUAN NILAI Sun Protection Factor (SPF) SECARA In Vitro
type: item
description: This study aims to determine the value of Sun Protection Factor (SPF) In Vitro Leaf Extract Ethanol Breadfruit (Artocarpus altilis) as a Material Sunscreen. The study design was an observational laboratory that carried out in the Laboratory Farmakognosi-fitokimia Study Pharmacy Faculty of Medicine and Health, Muhammadiyah University. In a study determining the SPF in vitro is done by making a solution of ethanol extract of leaves of breadfruit with a concentration of 25 ppm, 50 ppm, 100 ppm and 200 ppm were then the absorbance is measured using a UV-Vis spectrophotometer at a wavelength of 290-320 nm at intervals of 5 nm. The results showed that the ethanol extract of leaves of breadfruit at a concentration of 25 ppm by 1600, 50 ppm at 2.5966, 6.9166 at 100 ppm, and 200 ppm of 50.6811. Based on the results of this study concluded that the ethanol extract of leaves of breadfruit can be used as a sunscreen active ingredient in concentrations above 50 ppm (SPF value> 2).
subject: Articles
  topic: section
creator: Ainun Jariah
creator: muhammad taufiq dupppa
creator: Anshari Masri
creator: Wira Yustika Rukman
creator: Muhammad Guntur
creator: Andi Budirohmi
rights: Copyright (c) 2025 muhammad taufiq dupppa
date: 2025-07-31
publication date: 2025-07-31
starting page: 132
ending page: 139
doi: 10.59060/jurkes.v9i2.384

UJI EFEKTIVITAS EKSTRAK ETANOL BUAH BINTARO (Cerbera odollam Gaerthn) TERHADAP PENURUNAN GLUKOSA DARAH PADA TIKUS PUTIH (Rattus norvegicus)
type: item
description: This study aims to determine the efectivity of Bintaro Fruit (Cerbera odollam gaerthn) Ethanol Extract Against Blood Glucose Decrease in White Rats (Rattus Norvegicus. The research design used was an experimental laboratory carried out in the pharmacology laboratory of the Department of Pharmacy, Pancasakti University. This study used 15 rats. male white rats were divided into 5 groups consisting of group I as a negative control by giving 1% w/v Na.CMC suspension, groups II, III, IV as a treatment group given Bintaro Fruit extract 1% w/v, 3% w/v, 5% w/v And group V was given Glibenclamide suspension as a positive control.The results showed that the percentage reduction in blood glucose for negative control, treatment and positive groups was 11.37%, 32.03%, 65, respectively. 46%, 86.15%, 95.5% The most effective concentration was 5% w/v concentration with an average value of 86.15% reduction, but it has not been able to match the effectiveness of Glibenclamide. in statistical testing using the Graphad Prims program for an alpha rate of 0.05, P value of 0.0001 is significant, the F value is 608.3.
subject: Articles
  topic: section
creator: Anshari Masri
creator: muhammad taufiq dupppa
creator: Wira Yustika Rukman
creator: Syafruddin
creator: Sitti Nurjannah
creator: Delvi Sara JIhan
creator: Ermawati
rights: Copyright (c) 2025 muhammad taufiq dupppa
date: 2025-08-01
publication date: 2025-08-01
starting page: 140
ending page: 147
doi: 10.59060/jurkes.v9i2.386

EVALUASI MUTU FISIK DAN UJI IRITASI KOSMETIKA LULUR DENGAN MEMANFAATKAN BONGGOL NANAS SEBAGAI BAHAN AKTIF
type: item
description: The pineapple variety used in this research was queen pineapple. Pineapple processing produces waste in the form of pineapple tubers. The aim of this research is to make cosmetic scrubs with the active ingredient queen variety pineapple weevil (Ananas cosmosus L) and to determine the results of physical quality tests and determine the safety/irritation of body scrub preparations from pineapple weevils. This scrub preparation is made with three formulas using different concentrations of pineapple weevil powder, namely 5%, 7% and 9%. Physical quality tests of scrub preparations include organoleptic tests, homogeneity tests, pH tests and spreadability tests. Based on the results of the physical quality test, it shows that the formula with a pineapple weevil active substance concentration of 5% and the formula with a pineapple weevil active substance concentration of 7% is a formula that meets the physical quality test standards. Irritation/safety tests were carried out on rabbits and showed that the scrub preparation did not cause irritation, the degree index produced for all preparations tested was 0 (no irritation)
subject: Articles
  topic: section
creator: Suhartini
creator: Rina Bintoro
creator: Nurhidayat
rights: Copyright (c) 2025 Suhartini tansri
date: 2025-08-03
publication date: 2025-08-03
starting page: 90
ending page: 103
doi: 10.59060/jurkes.v9i2.372

PEMBUATAN DAN UJI MUTU FISIK SEDIAAN FACE MIST EKSTRAK DAUN ALPUKAT (Persea americana Mill.)
type: item
description: Avocado leaves are known to contain various bioactive compounds such as flavonoids, saponins, tannins, alkaloids, and phenols that are beneficial for skin health. This study refers to several literatures indicating that avocado leaf extract (Persea americana Mill.) exhibits significant antioxidant and antibacterial activities, which is why it was used as the active ingredient in the preparation of face mist. The aim of this research was to determine the physical quality of face mist formulations made with avocado leaf extract at concentrations of 0% (F0), 5% (F1), 7.5% (F2), and 10% (F3). The study was conducted experimentally in the laboratory, where the avocado leaf extract was obtained through maceration using 96% ethanol as the solvent. Physical quality tests performed included organoleptic evaluation, homogeneity test, pH measurement, spray distribution test, drying time test, and viscosity test. The results showed that avocado leaf extract (Persea americana Mill.) can be formulated into face mist preparations at concentrations of 5%, 7.5%, and 10%, all of which met the physical quality standards for face mist products.
subject: Articles
  topic: section
creator: Sukirawati
creator: Yusriyani Burhamin
creator: Nur Afifah Kamas
rights: Copyright (c) 2025 sukirawati sukirawati
date: 2025-08-04
publication date: 2025-08-04
starting page: 148
ending page: 157
doi: 10.59060/jurkes.v9i2.397