PEMBUATAN DAN UJI MUTU FISIK KRIM EKSTRAK HERBA PEGAGAN (Centella asiatica) (L.)

  • dzulasfi akfar yamasi
  • Suhartini Akademi Farmasi Yamasi Makassar
  • Agha Izha Fahiza Akademi Farmasi Yamasi Makassar

Abstrak

This study aims to make and test the Physical Quality Test of Centtella asiatica (L) extract of Centtella asiatica (L) in cream dosage forms with 0.5% and 1% extract concentrations. The type of research carried out is a laboratory experimental research by making Centella asiatica (L) herbal cream and testing the physical quality of the cream by conducting organoleptic, homogeneity, pH and dispersibility tests. The results of the observation of the pH test at a concentration of 0.5% is 6.13, a concentration of 1% is 6.47 while the dispersion test at a concentration of 0.5% is 5.1 cm, and a concentration of 1% is 5.2 cm. The results of the research on making and testing the physical quality of the cream of gotu kola herb extract 0.5% and 1% met the requirements for the physical quality test of cream preparations.

Referensi

Afrianti, R., Ramadheni, P., & Irsanti, P. N. (2017). Uji aktivitas estrogenik ekstrak etanol jintan hitam (Nigella sativa L.) terhadap perkembangan uterus tikus putih betina. Scientia, 7(1), 49–55.
Allen, L. (2014). Ansel’s Pharmaceutical Dosage Forms and Drug Delivery Systems. Wolters Kluwer Health. https://books.google.co.id/books?id=kepHAwAAQBAJ
Allen, L. V. (1998). The art, science, and technology of pharmaceutical compounding (Vol. 2). American Pharmaceutical Association Washington, DC.
Brotosisworo, S. (1979). Obat Hayati Golongan Glikosida. Universitas Gadjah Mada, Yogyakarta. Hlm, 44–45.
Ermawati, E. (2020). Formulasi Dan Uji Daya Hambat Krim Ekstrak Buah Pepaya (Carica papaya L.) Terhadap Propionibacterium acnes. Jurnal Kesehatan Yamasi Makassar, 4(1).
Parwanto, M. L. E., Mahyunis, S. H., & Edy, H. J. (2016). Syamsurizal. Fractination and Characterization of Proteins in Lumbricus rubellus Powders. Int J Pharm Clin Res, 8(1), 15–21.
Permenkes RI: No. 007 Tahun 2012 Tentang Registrasi Obat Tradisional, Peraturan Menteri Kesehatan Republik Indonesia. Jakarta (2012).
Rasyadi, Y., Rahim, F., & Putri, D. E. (2019). Uji aktivitas antibakteri sediaan kumur (mouthwash) dari ekstrak daun sukun Artocarpus altilis (Parkinson ex FA Zorn) Fosberg terhadap pertumbuhan bakteri Streptococcus mutans. Scientia: Jurnal Farmasi Dan Kesehatan, 9(1), 24–28.
Saryanti, D., Setiawan, I., & Safitri, R. A. (2019). Optimasi Asam Stearat dan Tea pada Formula Sediaan Krim Ekstrak Kulit Pisang Kepok (Musa Paradisiaca L.). Jurnal Riset Kefarmasian Indonesia, 1(3), 225–237.
Sikareepaisan, P., Suksamrarn, A., & Supaphol, P. (2007). Electrospun gelatin fiber mats containing a herbal—Centella asiatica—extract and release characteristic of asiaticoside. Nanotechnology, 19(1), 015102.
Sulastri, L., Indriaty, S., & Pandanwangi, S. (2017). Formulasi dan uji iritasi dari krim yang mengandung ekstrak etanol herba pegagan (Centella asiatica (L) Urban). Medical Sains: Jurnal Ilmiah Kefarmasian, 1(2), 67–75
Diterbitkan
2023-08-01
Bagian
Articles