UJI EFEK ANALGESIK EKSTRAK ETANOL UMBI BAWANG DAYAK (Eleutherine americana L. Merr) PADA MENCIT JANTAN (Mus musculus)

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  • Taufiq Taufiq AKADEMI FARMASI YAMASI

Abstract

This study was conducted to determine the analgesic effect of the ethanolic extract of Dayak onion bulbs (Eleutherinr americana L. Merr) on male mice (Mus musculus). 15 adult male mice were used which were divided into 5 groups and each group consisted of 3 animals with stretching observation time from 5 minutes to 60 minutes. Group I was given 1% Na CMC as a negative control, group II, III, and IV were given ethanol extract of Dayak Onion Bulbs with extract doses of 1.17 mg/0.5 ml, 2.34 mg/0.5 ml, and 4.68 mg/0.5 ml with a volume of 1 ml /30-gram BW orally with a volume of 1 ml/30 g body weight of mice. The results of the study on the administration of Dayak onion bulb extract (Eleutherine americana L. Merr) with extract doses of 1.17 mg/0.5 ml, 2.34 mg/0.5 ml, and 4.68 mg/0.5 ml, respectively. -the average percentage of stretching (19.48 %), (36.02 %), (62.11% %), while the administration of mefenamic acid suspension was 1.3 g/0.5 ml, the percentage of stretching was (76 ,48 %). Statistical test using SPSS 25 with the one way ANOVA method on the LSD follow-up test to see whether there is a difference in the analgesic effect of the extract shows a significant value of 0.000 (p < 0.005), which means that there is a significant difference between treatments (significant), at a confidence level of 5 % (α = 0.05).

Author Biography

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Jurnal Kesehatan Yamasi Makassar merupakan wadah bagi peneliti untuk mengimplementasikan hasil karya ilmiah sebagai tuntutan Tri Dharma Perguruan Tinggi. Jurnal ini terbit dua kali dalam setahun, yaitu setiap bulan Januari dan Juli. Apresiasi dan penghargaan yang tinggi kepada peneliti atas kepercayaannya untuk mempublikasikan hasil penelitian di jurnal ini. Semoga jurnal ini dapat bermanfaat sebagai media danwadah informasi untuk kemajuan dan perkembangan dunia teknologi kesehatan dan farmasi. 

References

Dayak Onion Bulbs
Extract
Stretching
Mice
Published
2022-01-31