PEMBUATAN DAN UJI MUTU SEDIAAN GEL HAND SANITIZER EKSTRAK ETANOL DAUN MATOA (Pometia pinnata J.R & G. FORST)

Abstract

Matoa leaves contain phytochemical compounds, in the form of secondary metabolite compounds such as flavonoids, alkaloids, tannins, saponins, terpenoids and coumarins. Secondary metabolite compounds are defined as antioxidant compounds whose role is to ward off free radicals. This research aims to determine the manufacture and physical quality testing of hand sanitizer gel preparations from matoa leaf extract (Pometia pinnata J.R & G. FORST). The research method used was experimental laboratory by conducting experiments for making hand sanitizer gel preparations and physical quality tests on the preparations carried out in the teaching factory laboratory of the Yamasi Pharmacy Academy, Makassar. Matoa leaves (Pometia pinnata J.R & G. FORST) were extracted by maceration for 1×24 hours using 96% ethanol solvent. Hand sanitizer gel preparations were made in negative control and 3 concentration formulas of 2%, 3% and 4%. The physical quality tests carried out are organoleptic test, homogeneity test, PH test, spreadability test. The research results stated that matoa leaf extract (Pometia pinnata J.R & G. FORST) could be made into hand sanitizer gel preparations with concentrations of 2%, 3% and 4%, and met the requirements for good physical quality tests and irritation tests for hand sanitizer gel preparations.