Jurnal Kesehatan Yamasi Makassar

TINGKAT KEPATUHAN MINUM OBAT ANTIDIABETES PASIEN DIABETES MELITUS TIPE II DI PUSKESMAS KARTASURA SUKOHARJO

Ifki Isnaini — 2024-07-30

Diabetes mellitus (DM) is a serious long-term (or chronic) condition that occurs when there is an increase in glucose levels in the blood because the body cannot produce enough of the insulin hormone, or cannot use the insulin it produces effectively. The aim of this study was to determine the level of compliance with taking oral antidiabetic medication in patients with type II diabetes mellitus at the Kartasura Sukoharjo Community Health Center. The research method uses descriptive quantitative with prospective data collection. The research was conducted at the Kartasura Sukoharjo Community Health Center in December 2023 - January 2024. The instrument used was MARS-5 which consists of 5 questions that describe the patient's level of medication adherence. The sampling technique used purposive sampling (non probability sampling) of 120 samples. Based on the research results obtained, it can be concluded that the level of compliance with taking antidiabetic medication for type II diabetes mellitus patients is in the high level of compliance category with 9 respondents (7.5%), the medium level of compliance category is 111 respondents (92.5%), category low compliance level of 0 respondents (0%).

IDENTIFIKASI KANDUNGAN METABOLIT SEKUNDER PADA DAUN SERAI WANGI (Cymbopogon nardus L. Rendle) DI KABUPATEN BANYUMAS

sri royani — 2024-07-31

Citronella or Cymbopogon nardus L. Rendle is one of the plants that grows abundantly in Indonesia. In addition to being used as a culinary ingredient, citronella is also widely used as a family medicinal plant. This study aimed to identify the secondary metabolite content in citronella leaf extract. The results of the test showed that citronella contains secondary metabolites in the form of flavonoids, alkaloids, tannins, and saponins.

ANALISIS ASAM LEMAK BEBAS DAN KADAR AIR MENGGUNAKAN ADSORBEN KUNYIT DENGAN PENGARUH LAMA WAKTU ADSORPSI

Linda Duwi Febriyanti — 2024-08-01

Cooking oil is one of the daily necessities for people. Repeated use of cooking oil can pose health risks due to the presence of potentially harmful compounds. The quality of cooking oil can be assessed based on its free fatty acid level and moisture content, with SNI 7709:2019 setting maximum standards of 0,3% for free fatty acid level and 0,1% for moisture content. Therefore, there is a need to reduce the levels of free fatty acid and moisture content in used cooking oil. One of the methods that can be used is adsorption using turmeric powder as adsorbent. The research aims to investigate how varying adoption times affect moisture content and free fatty acid levels in used cooking oil. The results indicate that turmeric is capable of reducing the free fatty acids and moisture content in used cooking oil. This study reveals that the free fatty acid decreases with increasing adsorption time of 35, 45, 50, 55, and 60 minutes, yielding values 0,881; 0,794; 0,706; 0,618; and 0,559%, respectively. The moisture content results with adsorption times of 35, 45, 50, dan 55 minutes were 0,120; 0,101; 0,095, and 0,080 %, respectively. The optimal reduction in free fatty acids occurs at 60 minutes of adsorption, with a decrease of 45,08%. The best reduction in moisture content is achieved at 55 minutes of adsorption, with a decrease of 40,74%.

FORMULASI DAN UJI STABILITAS FISIK FACIAL WASH EKSTRAK ETANOL DAUN KITOLOD (Isotoma longiflora L.) SERTA AKTIVITASNYA TERHADAP Staphylococcus epidermidis

Hernawati Basir — 2024-07-31

Daun kitolod merupakan tumbuhan yang jarang dilirik oleh masyarakat secara umum, tumbuhan ini tumbuh liar dan mudah ditemukan. Daun kitolod (Isotoma longiflora L.) mengandung senyawa seperti flavonoid, alkaloid, saponin, dan politerol. Penelitian ini bertujuan untuk memformulasi sediaan facial wash ekstrak etanol daun kitolod dan uji stabilitas fisik serta menguji aktivitasnya terhadap Staphylococcus epidermidis. Metode yang digunakan pada penelitian ini adalah eksperimental laboratorium dimana dilakukan uji stabilitas fisik sediaan facial wash ekstrak etanol daun kitolod (Isotoma longiflora L.) berupa uji organoleptik, pH, homogenitas, daya sebar, daya busa, viskositas, iritasi terhadap kulit, stabilitas penyimpanan, dan aktivitasnya terhadap Staphylococcus epidermidis. Ekstrak etanol daun kitolod (Isotoma longiflora L.) kemudian diformulasikan menjadi sediaan facial wash yang dibuat dalam 3 formulasi yaitu F0:0%, F1:15%, F2:20%. Berdasarkan hasil uji stabilitas fisik Hasil evaluasi uji pH F0, F1, dan F2 berurut adalah 5,3; 5,1 dan 5,1. Hasil uji homogenitas semua formulasi menunjukkan bahwa sediaan homogen. Hasil viskositas F0, F1, dan F2 berurut yaitu 1100 cPs; 553,3 cPs dan 600 Cps. Hasil uji iritasi pada kulit dengan enam sukarelawan menunjukkan tidak terjadi iritasi pada kulit,, hasil uji stabilitas penyimpanan selama 6 siklus atau 12 hari penyimpanan pada suhu bergantian 4°C dan 40°C sediaan tetap stabil, sedangkan pada pengujian aktivitasnya terhadap Staphylococcus epidermidis pada formulasi F1 dan F2 menunjukkan hasil memiliki daya hambat dalam kategori kuat.

UJI EFEKTIVITAS SEDIAAN KRIM EKSTRAK ETANOL BIJI PINANG (Areca cathecu L) SEBAGAI OBAT LUKA SAYAT PADA KELINCI (Oryctolagus cuniculus)

dzulasfi — 2024-08-01

This study aims to determine the effectiveness of areca nut ethanol extract cream on healing incision wounds in rabbits. This study is an experimental study in the Laboratory using 1%, 2%, and 3% areca nut extract cream as test samples and betadine cream as a positive control and cream base as a negative control tested on rabbits. The results of this study obtained a wound healing effect on betel nut extract cream 1% by (4,25%) per day, betel nut extract cream 2% by (6,00%) per day, and betel nut extract cream 3% by (6.75%) per day.

TINGKAT KEPATUHAN PENGGUNAAN OBAT PADA PASIEN TB PARU DI KLINIK WIRAHUSADA MEDICAL CENTER KOTA MAKASSAR

Muhammad Tahir — 2024-08-01

One of the most common infectious diseases in the world is tuberculosis (TB). This disease is caused by the bacterium Mycobacterium tuberculosis. The research conducted included descriptive research using a cross-sectional approach. This study was carried out at Klinik Wirahusada Medical Center in Makassar City in June-July 2023. The population in this study consisted of pulmonary Tuberculosis (TB) patients at Klinik Wirahusada Medical Center in June-July 2023 who were using Anti Tuberculosis Drugs (OAT) for the treatment of pulmonary Tuberculosis (TB) and agreed to participate as respondents. The research sample used all populations (total sampling). Data collection was done using questionnaires by providing written questions to the patients. Data processing was done descriptively, with the data resulting in percentages and calculated by multiplying the respondents' answers by one. 60 respondents were obtained. Out of 60 respondents, 63% were male, and 37% were female. Based on the questionnaire, there were 36 individuals with a high compliance level representing 60%, 15 individuals with a moderate compliance level representing 25%, and 9 individuals with a low compliance level representing 15%.

PEMBUATAN DAN UJI MUTU FISIK SEDIAAN BALSAM STIK EKSTRAK DAUN KEMANGI (Ocimum basilicum L.)

taufiq taufiq — 2024-08-01

Balsam stick is an innovative alternative preparation of balsam preparations to increase user comfort and ease of use. The aim of this research was to determine whether basil leaves (Ocimum basilicum L.) could be formulated in the form of stick balm. This research uses experimental research methods. By using various concentration variants starting from 1%, 3% and 5% formulations using several evaluation tests for balm preparations including organoleptic tests, homogeneity tests, pH tests, spreadability tests and adhesion tests. The research results obtained for the organoleptic test in the form of pH showed that the pH test results produced a pH of 6 and were homogeneous for each concentration. In the organoleptic test, it has a semi-solid form, has a distinctive aroma of basil leaves and has a light green color at a concentration of 1% and a dark green color at a concentration of 3% and 5%. In the spreadability test, a concentration of 1% produced 5.4 cm, a concentration of 3% produced 6.1 cm and a concentration of 5% produced 5.6 cm. In the adhesion test at a concentration of 1%, adhesion was obtained for 12 seconds, at a concentration of 3% for 17 seconds, and at a concentration of 5%, adhesion was obtained for 7 seconds.

UJI DAYA HAMBAT SEDIAAN GEL EKSTRAK ETANOL DAUN MANGGA ARUM MANIS (Mangifera indica Linn.) TERHADAP PERTUMBUHAN Staphylococcus epidermidis

Maulana Zulkarnain Imansyah Maulana — 2024-08-09

The compounds contained in the leaves of the arum manis mango (Mangifera indica LINN.) are tannins, alkaloids, saponins, flavonoids and mangiferin which have antibacterial properties. This study aims to determine whether the ethanol extract gel preparation of mango arum manis (Mangifera indica LINN.) leaves has antibacterial inhibition against Staphylococcus epidermidis. Mango arummanis leaf extract was prepared in a gel preparation with a concentration of 15%, 20% and 25%. Testing the antibacterial activity of mango arummanis (Mangifera indica LINN.) leaf extract gel using the paperdisk method and agar medium (NA) as a medium and incubated for 1x24 hours at 37oC. Then observations were made by measuring the inhibition zone that occurred at each preparation concentration on the Staphylococcus epidermidis test bacteria. The results showed that the inhibition zone of the ethanol extract gel preparation of Mango Arum Manis (Mangifera indica LINN.) concentration of 15% showed an inhibition zone diameter of 5.03 mm, a concentration of 20% showed an inhibition zone diameter of 6.28 mm, a concentration of 25% showed an inhibition zone diameter of 7.04 mm with the results of inhibition of bacterial growth categorized as moderate (5-10mm). Whereas in the positive control of clindamycin ointment, the diameter of the inhibition zone was 26.59 mm with the result that the inhibition of bacterial growth was categorized as very strong. The conclusion of the study stated that the ethanol extract of mango arummanis leaves (Mangifera indica LINN.) with a concentration of 25% was better than concentrations of 15% and 20%.

PROFIL PERESEPAN OBAT PADA PASIEN DIABETER TIPE2 DI RSUD LABUANG BAJI MAKASSAR PROVINSI SULAWESI SELATAN PERIODE JANUARI DESEMBER 2023

Agust Dwi Djajanti Djajanti — 2024-08-09

Type 2 diabetes mellitus (DM) is a long-term disease that occurs when the body cannot use insulin effectively. Based on previous research data in 2022 for the January-December period, data was obtained on type 2 DM patients who received treatment at Labuang Baji Hospital, Makassar, South Sulawesi Province, as many as 145 people, so for this reason this research was carried out with the aim of knowing the profile of drug prescribing in diabetes patients. type 2 at Labuang Baji Hospital, Makassar, South Sulawesi Province for the period June-December 2023. This research uses descriptive research methods and retrospective data collection. The variables studied in the Type 2 DM drug prescribing profile are type of drug, dose, instructions for use and amount of drug. The total number of recipe data obtained was 125 recipes. The research results show that the most frequently prescribed type 2 DM drug is Glimepiride. The most frequently prescribed doses of type 2 DM drugs are Glimepiride 2mg, Metformin 500mg, Glibenclamide 5mg, Pioglitazone 30mg and Acarbose 50mg and 100mg. The rules for using type 2 DM that are most often prescribed are Glimepiride once a day, Metformin 3 times a day, Glibenclamide once a day, Pioglitazone once a day and Acarbose 3 times a day. The number of type 2 DM drugs most frequently prescribed are Glimepiride 30 tablets, Metformin 60 tablets, Glibenclamide 30 tablets, Pioglitazone 30 tablets and Acarbose 30 tablets.

KARAKTERISTIK KOMBUCHA KULIT BUAH KOPI ARABIKA (Coffea arabica L.) DENGAN BERBAGAI VARIAN RASA

Nurul Hidayah Base — 2024-08-13

Arabica coffee fruit skin (Cofea arabica L.) known as cascara is coffee waste which contains polyphenolic compounds which are antioxidants, which can be processed into processed products that are healthy for health, such as kombucha drinks as a result of fermentation from the symbiotic Scooby culture. This research aims to determine how to make and characterize the physical quality of Arabica coffee fruit skin kombucha with various flavor variants. This research is an experimental laboratory research by making kombucha tea from Arabica coffee fruit skin powder which is brewed in hot water, stored for 14 days. Adding sugar and Scoby, then physical quality characterization was carried out after being given flavor variants, namely original (F1), Strawberry (F2), Lemon (F3), Ginger (4) and Cinnamon (5). Kombucha tea Arabica coffee fruit skin has organoleptic characteristics with yellow (F1, F3, F4), red (F2), brownish yellow (F5); The distinctive aroma of each formula corresponds to the aroma of the additional ingredients provided; Sour taste (F1, F3, F4), slightly sweet sour (F2), sweet (F5). pH 3-4 and alcohol content of 0.3% (F1) and 0% (F2, F3, F4, F5). Kombucha tea made from Arabica coffee fruit skin has typical organoleptic characteristics, pH < 4.5 and alcohol content < 0.5%.

PEMBUATAN DAN UJI MUTU FISIK SEDIAAN PASTA GIGI ESKTRAK DAUN BIDARA ARAB (Ziziphus spina-christi L.) ASAL KABUPATEN GOWA

Muhammad Alfajri Samsuddin — 2024-08-15

Abstract. Toothpaste is one of the preparations that can be used in maintaining dental hygiene. Toothpaste can be made from natural ingredients, one of which is from the Arabian Bidara plant which has antibacterial properties. This study aims to make and test the physical quality of toothpaste preparations from bidara arabic leaf extract (Ziziphus Spina-Christi L.) with concentrations of 4% and 5%. Physical quality tests carried out include: Organoleptic test, homogeneity test, pH test and spreadability test. The results of this study state that the extract of Arabian Bidara leaves (Ziziphus Spina-Christi L.) can be made toothpaste preparations with concentrations of 4% and 5% which meet the requirements of the physical quality test of toothpaste preparations.

FORMULASI DAN UJI STABILITAS FISIK SEDIAAN MASKER GEL PEEL-OFF EKSTRAK ETANOL DAUN BAYAM MERAH (Amaranthus Tricolor L.) DENGAN BASIS POLIVINIL ALKOHOL

Rusmin Rusmin — 2024-08-15

Abstract. The purpose this study was to determine the effect of variations in PVA concentration on the physical characteristics of the peel off gel mask preparation and to determine the concentration of PVA in the peel off gel mask preparation of red spinach leaf extract which can provide good physical characteristics. Red spinach leaves contain flavonoid compounds, saponins and tannins which have antioksidant effect on the skin. Red spinach leaves extract was prepared in a peel off gel mask preparation by varying the concentration of PVA. PVA plays role in the formulation of peel off gel masks because it has adhesive properties. The concentrations of PVA used was 10% ^b/_b, 13% ^b/_b and 16% ^b/_b. Extraction of red spinach leaves was obtained by remaceration method using 96% ethanol as solvent. The physical characteristic tests, drying time test, stability tests, and viscosity tests. Based on the statistical results of One Way Anova the physical characteristics of the peel off gel mask preparation including pH, spread ability, viscosity and drying time, there was a significant difference of 0,000 (sig<0,05). The concentration of PVA in the peel off gel mask preparation of purple leaf extract which can provide good physical characteristics is the concentration of PVA at 13%.

PEMBUATAN DAN UJI MUTU SEDIAAN SERUM DARI EKSTRAK KULIT DURIAN (Durio zibethinus Murray)

Arief Azis — 2024-08-15

Kulit durian (Durio zibethinus Murray) mengandung senyawa aktif yaitu alkaloid, flavonoid, tanin, saponin, dan fenolik yang bersifat sebagai antibakteri dan antioksidan sehingga dapat digunakan sebagai alternatif bahan aktif untuk perawatan kulit wajah. Penelitian ini dilakukan dengan tujuan mengetahui pembuatan dan uji mutu terhadap sediaan serum ekstrak kulit durian (Durio zibethinus Murray) metode penelitian yang digunakan adalah eksperimental

laboratorium dengan melakukan percobaan pembuatan sediaan serum dan pengujian mutu fisik terhadap sediaan yang dilaksanakan di laboratorium Teaching Factory Akademi Farmasi Yamasi Makassar. Kulit durian (Durio zibethinus Murray) diekstraksi secara maserasi selama 3x24 jam dengan menggunakan pelarut etanol 96%. Sediaan serum dibuat dalam bentuk kontrol negatif dan 3 formula konsentrasi 10%,15%, dan 20%. Uji mutu yang dilakukan meliputi uji organoleptik, homogenitas, pH, daya sebar, daya lekat, dan waktu kering. Hasil penelitian menunjukkan bahwa ekstrak kulit durian (Durio zibethinus Murray) dapat dibuat sediaan serum dengan konsentrasi 10%,15%, dan 20%, serta memenuhi syarat uji mutu fisik sediaan serum yang baik.

PERBANDINGAN PENGGUNAAN AMLODIPINE DAN KOMBINASI AMLODIPINE DENGAN CANDESARTAN PADA PENDERITA HIPERTENSI DI APOTEK KIMIA FARMA ALAUDDIN MAKASSAR JULI-DESEMBER 2023

sukirawati sukirawati — 2024-08-15

PEMBUATAN DAN UJI MUTU FISIK SEDIAAN TONER WAJAH INFUSA DAUN BELIMBING WULUH (Avverhoa bilimbi L.)

Yusriyani Burhamin — 2024-08-19

Abstract. Facial toner research has been carried out using samples of starfruit leaves (Avverhoa Bilimbi L.) originating from Pinrang, South Sulawesi. The research was carried out with the aim of knowing the manufacture and quality testing of facial toner preparations from the infusion extract of starfruit leaves (Avverhoa bilimbi L). Simplisia starfruit leaves are extracted using the infusion method. This formula is made with a base (without extract) and concentrations of 10%, 20% and 30%. Physical quality tests carried out on facial toner preparations are organoleptic tests, pH tests, homogeneity tests and irritation tests. Organoleptic Results F0, F1, F2, F3 have liquid form, characteristic odor and are brown in color. The results of the pH test, homogeneity test and irritation test on the 10 panelists met the requirements because there was no irritation, itching or swelling on the skin.

UJI AKTIVITAS GEL HAND SANITIZER EKSTRAK ETANOL BUAH BIDARA CINA (Ziziphus jujuba) TERHADAP PERTUMBUHAN Escherichia coli

Zakiah Thahir — 2024-08-19

Hand sanitizer gel is an antiseptic product to prevent and kill microorganisms on the palm of the hand. Natural ingredients can also be used as antibacterial substances and are considered safer than chemicals because natural ingredients have smaller side effects. In addition, natural ingredients are very easy to obtain by the community to be used as an alternative to antibacterial substances in reducing bacterial infections on the skin. One of them is Chinese bidara fruit (Zizipus jujuba). This study aims to determine the effectiveness of hand sanitizer gel ethanol extract of Chinese bidara fruit (Zizipus Jujuba) against the growth of Escherichia coli In this study, a hand sanitizer gel formula was made with a concentration ratio of bidara fruit extract 2.5, 3, and 3.5%. Antimicrobial activity was tested using the disc diffusion method. The results obtained show that the ethanol extract gel of Chinese bidara fruit (Zizipus jujuba) can inhibit the growth of Escherichia coli with a strong effectiveness of 19.6 mm at an extract concentration of 3.5%.