Jurnal Kesehatan Yamasi Makassar

GAMBARAN SISTEM PENYIMPANAN OBAT DI PUSKESMAS GALESONG UTARA KECAMATAN GALESONG UTARA KABUPATEN TAKALAR

Muhammad Tahir Muhammad Tahir — 2024-01-30

Research has been carried out at the North Galesong Health Center, North Galesong District, Takalar Regency to find out the description of the Drug Storage System in the Health Center. This research was conducted by direct interviews and is descriptive in nature. Apt. Hj. Kartini, S. Farm. As the Person in Charge of the Pharmacy stated that the drug storage at North Galesong Health Center had met the existing storage standards starting from the drugs being arranged alphabetically for each dosage form, the drugs being stored on the floor placed on pallets, the method of storing drugs that met the requirements such as the drugs being rotated with the FEFO (First Expired First Out) and FIFO (First In First Out) systems, liquids, ointments and injectable drugs were stored in the center of the shelf, drugs that required cold temperatures were stored in the refrigerator, there were no expired drugs in the drug store, desinfe ctan is placed separately from other drugs, drugs that have the same expiration date are used which arrive first, there are no drugs that are of poor quality, drugs that have a similar appearance and name (LASA; Look Alike Sound Alike) are not placed close together, liquid drugs are separated from solid drugs

UJI MUTU VIRGIN COCONUT OIL (VCO) DENGAN METODE FERMENTASI DAN PEMANCINGAN

A Tenriugi Daeng Pine — 2024-01-30

Quality test research has been carried out with the aim of knowing the physical quality of VCO preparations made using hybrid coconut. The research method used was laboratory experimental by conducting physical quality tests on preparations carried out at the Natural Materials Technology Laboratory and Pharmaceutical Chemistry Laboratory at the Yamasi Pharmacy Academy, Makassar. Hybrid coconut is made in the form of coconut cream then the cream is made into VCO preparations using two methods, namely the fermentation method and the fishing method. The physical quality tests carried out included organoleptic tests, water content, free fatty acids and peroxide numbers. The results of this study stated that from the two methods of making VCO, the baiting method gave better results than the fermentation method, namely the fishing method produced a yield of 41.4% , organoleptic (specific smell of coconut aroma, typical taste of coconut oil and clear color) water content of 0.049%, free fatty acids 0.1% and peroxide value 10.8 mg ek/k. Whereas the fermentation method produced a yield of 29.3%, organoleptic (typical coconut aroma, distinctive coconut oil taste and clear color), 0.029% water content, 0.45% free fatty acids and 4.2 mg oak/k peroxide.

UJI ANGKA KAPANG KHAMIR DAN ANGKA LEMPENG TOTAL PADA WEDANG UWUH YANG DIKOMBINASIKAN DENGAN BUAH MAHKOTA DEWA (Phaleria macrocarpa L.)

Rusmin Rusmin — 2024-02-09

Abstrak. Penelitian ini bertujuan untuk mengetahui angka kapang khamir dan angka lempeng total pada wedang uwuh yang dikombinasikan dengan buah mahkota dewa. Desain penelitian yang digunakan adalah eksperimental laboratorium yang dilaksanakan di Laboratorium Mikrobiologi Akademi Farmasi Yamasi Makassar. Penelitian ini menggunakan wedang uwuh yang dikombinasikan dengan buah mahkota dewa yang diuji terhadap angka kapang khamir dan angka lempeng total sebagai parameter persyaratan mutu obat tradisional di Indonesia. Pengujian dilakukan selama 2 pekan yang dimana angka pencatatan angka kapang khamir dilihat pada hari ke lima, dan angka lempeng total dilihat pada hari ke tiga di setiap pekannya. Hasil penelitian menunjukkan bahwa pada uji angka kapang khamir, pekan pertama pada pengenceran 10^-4 sejumlah 2 x 10⁴, dan pada pekan kedua pengenceran 10^-4 sejumlah <10. Sedangkan pada uji angka lempeng total, pekan pertama pada pengenceran 10^-6 sejumlah <10, dan pada pekan kedua pengenceran 10^-6sejumlah 6 x 10⁵. Setelah dilakukan standarisasi terhadap peraturan BPOM no 12 tahun 2014 disimpulkan bahwa sediaan wedang uwuh yang dikombinasikan dengan buah mahkota dewa aman untuk dikonsumsi pada parameter angka kapang khamir dan angka lempeng total.

Kata Kunci :

Wedang uwuh
Mahkota dewa ,
Angka kapang khamir
Angka lempeng total

UJI HEDONIK SEDIAAN KOSMETIK ARANG AKTIF BAMBU KUNING (Bambusa vulgaris var. Striata)

Raymond Arief N Noena — 2024-02-09

Telah dilakukan penelitian yaitu Uji hedonik sediaan sabun, lulur dan pasta gigi berbahan dasar charcoal atau arang aktif bambu kuning (Bambusa vulgaris var. Striata) dengan tujuan untuk mengetahui tingkat kesukaan panelis terhadap kosmetik herbal dengan pembanding sediaan herbal sejenis yang beredar di pasaran. Uji hedonik dilakukan terhadap warna aroma, rasa, tekstur dan kemasan dan melibatkan panelis sebanyak 30 orang. Hasil penelitian menunjukkan bahwa tingkat kesukaan panelis terhadap sediaan kosmetika berturut turut sebagai berikut : pasta gigi (4,22), sabun sebesar (4,03) dan lulur (3,86) Jadi sediaan kosmetik berbahan dasar arang aktif bambu kuning memiliki potensi untuk dikembangkan menjadi sediaan kosmetik herbal modern.

AKTIVITAS SIRUP EKSTRAK KULIT BUAH RAMBUTAN (Nephelium lappaceum L.) TERHADAP KADAR KOLESTEROL TOTAL DARAH MENCIT (Mus musculus)

Agust Dwi Djajanti Djajanti — 2024-02-09

This study aims to determine the “Activity of syrup ekstrak from Rambutan Peel (Nephelium lappaceum L.) on reducing total cholesterol levels in the blood of mice (Mus musculus).” This type of research using the pre and post test method. Induction of hypercholesterolemia was carried out by giving high-fat feed, namely duck egg yolk and butter and PTU inducers which were given every day at relatively the same time for 14 days by oral method. On the 15^th day the mice were fasted but still given to drink for the next 3 hours. Cholesterol levels were measured after induction for 14 days (induction cholesterol levels). The mice test animals used were 6 mice (Mus musculus) which were divided into 2 treatment groups. On day 15, groups 1 was treated with gemfibrozil 300 mg as a positive control and group 2 was treated with syrup of rambutan peel extract. After 30 minutes, the mice’s cholesterol levels were meansured. On day 16 they were given the same treatment on day 15 and cholesterol levels were menasured 30 minutes after administration. From the results of the study it was concluded that administration of syrup of rambutan peel extract (Naphaleum lappaeum L.) with a level of 250 mg/ml can reduce total cholesterol levels in the blood of mice with an average decrease of 7% and 11%.

UJI DAYA HAMBAT SEDIAAN KRIM EKSTRAK ETANOL BIJI PINANG (Areca cathecu L.) TERHADAP Staphylococcus aureus

dzulasfi — 2024-02-09

Tujuan dari penelitian ini adalah untuk mengetahui apakah krim ekstrak etanol biji pinang (Areca cathecu L) dapat menghambat pertumbuhan Staphylococcus aureus. Jenis penelitian yang dilakukan adalah jenis penelitian eksperimen Laboratorium, dengan melakukan uji daya hambat sediaan krim ekstrak etanol biji pinang terhadap Staphylococcus aureus. Di simpulkan bahwa krim ekstrak etanol biji pinang dapat menghambat pertumbuhan Staphylococcus aureus dengan diameter zona hambatan untuk konsentasi 1% sebesar 6,55 mm, konsentasi 2% sebesar 11,4 mm, konsentrasi 3% sebesar 16,5 mm, kontrol negatif 0 mm, dan kontrol positif 26,62 mm.

UJI DAYA HAMBAT SEDIAAN SABUN PADAT EKSTRAK ETANOL DAUN MANGGA ARUM MANIS (Mangifera indica .LINN) TERHADAP BAKTERI Staphylococcus aureus

Maulana Zulkarnain Imansyah Maulana — 2024-02-09

Obat Tradisional adalah bahan atau ramuan bahan yang berupa bahan tumbuhan, bahan hewan, bahan mineral, sediaan galenik atau campuran dan bahan-bahan tersebut, yang secara tradisional telah digunakan untuk pengobatan berdasarkan pengalaman. Salah satu tanaman yang dapat dijadikan sebagai obat tradisional adalah daun mangga arum manis (Mangifera indica LINN.). Daun Mangga Arum Manis yang biasa dijumpai ternyata akan kaya manfaat bagi kesehatan. Senyawa yang terkandung dalam daun mangga arum manis yaitu tannin alkaloid, flavonoid, saponin dan mangiferin yang memiliki khasiat sebagai antibakteri. Penelitian ini bertujuan untuk mengetahui daya hambat pada sediaan sabun padat ekstrak daun mangga arum manis terhadap bakteri Staphylococcus aureus. Sabun padat dibuat dalam 3 konsentrasi yaitu 1%, 2% dan 3%, kemudian dilakukan uji zona hambat pada bakteri Staphylococcus aureus dengan metode paper disk, kontrol negatif menggunakan basis sabun padat tanpa ekstrak dan kontrol positif menggunakan sabun padat antiseptic yang beredar di pasaran. Hasil yang diperoleh yaitu Rata-rata diameter hambatan dari sabun padat dengan konsentrasi 1% yaitu 1,93 mm, konsentrasi 2% yaitu 10,36 mm sedangkan konsentrasi 3% yaitu 12,68 mm. Berdasarkan hasil penelitian yang diperoleh dapat disimpulkan bahwa sabun padat ekstrak etanol daun mangga arum manis dapat menghambat pertumbuhan bakteri Staphylococcus aureus.

EFEKTIVITAS SEDIAAN SERUM WAJAH EKSTRAK RAMBUT JAGUNG (Zea mays L.) TERHADAP Propionibacterium acne

ananda ramadani — 2024-02-09

This study aims to determine the effectiveness of facial serum preparations of corn hair extract (Zea mays L.) on the growth of Propionibacterium acnes. The research method used was experimental laboratory research, to determine the effectiveness of corn silk extract serum (Zea mays L.) against Propionibacterium acnes which was carried out at the Microbiology Laboratory of the Yamasi Pharmacy Academy, Makassar. Corn silk (Zea mays L.) was extracted using the maceration method using 96% ethanol solvent, the extract obtained was then made into a serum preparation with a concentration of (F1) 6% w/w, (F2) 8% w/w, (F3) 10% w/w and (F4) as serum base. The results of the study stated that corn hair extract (Zea mays L.) with a concentration of 10% was more effective in inhibiting the growth of Propionibacterium acnes

Abdiana, R. (2017 ). Rambut Jagung (Zea mays L.) Sebagai alternatif Tabir Surya Corn Silk As An Alternatif to sunscreen. Indonesia journal of pharmaceutical Science and Technology, 31-35.

Alfianti, A. A. (2020). Aktivitas Sediaan Gel Handsanitizer Ekstrak Etanol Limbah Rambut Jagung (Zea Mays L.) Terhadap Staphylococcus Aureus. Univeristas Muslim Nusantara Al-Washliyah.

Fajrina, A., Dinni, D., Bakhtra, A., Eriadi, A., Chania Putri, W., & Wahyuni, S. (2021). Uji Aktivitas Antibakteri Ekstrak Etanol Rambut Jagung (Zea maysL.) Terhadap Bakteri Streptococcus mutansdan Porphyromonas gingivalis. Jurnal Farmasi Higea, 13(2).

Harunnisa, Kartikasari, D., Rahman, I. R., & Kurnianti, E. (2022). Formulasi Sediaan Serum Ekstrak Etanol Kulit Buah Tampoi (Baccaurea macrocarpa) Sebagai Antioksidan Dengan Variasi Konsentrasi Ekstrak. Ilmiah Pharmacy, 9(2), 11–23.

Hasrawati, A., Hardianti, H., Qama, A., & Wais, M. (2020). Pengembangan Ekstrak Etanol Limbah Biji Pepaya (Carica papaya L.) Sebagai Serum Antijerawat. Jurnal Fitofarmaka Indonesia, 7(1), 1–8.

https://doi.org/10.33096/jffi.v7i1.458.

Ismiati, E. R. (2015). Aktivitas Antioksidan Minuman Herbal Rambut Jagung dengan Variasi Kondisi dan Lama Perebusan. Universitas Muhammadiyah Surakarta.

kusriani, H. M. (2017 ). aktivitas antioksidan dan tabir surya dari tongkol dan rambut jagung (Zea mays L.) . sekolah tinggi farmasi bandung vol 4.

nurbaity.(2020). Efektivitas Ekstrak Etanol Daun Arika (Vernonia amigdalina Del.) Terhadap Bakteri Staphylococcus aureus. Universitas Muhammadiyah Magelang , 6-9.

Yanti, N. R. (2020). Aktivitas Sediaan Gel Anti Acne Ekstrak Etanol Limbah Rambut Jagung (Zea Mays L.) Terhadap Propionibacterium Acnes. Universitas Muslim Nusantara Al-Washliyah

UJI IRITASI SEDIAAN KRIM EKSTRAK ETANOL DAUN CENGKEH (Syzygium aromaticum L.) TERHADAP MENCIT (Mus musculus)

Arief Azis — 2024-02-09

This study aims to determine the irritating effect of clove leaf ethanol extract cream (Syzygium aromaticum L.) on mice (Mus musculus) and at what concentration clove leaf extract (Syzygium aromaticum L.) can cause irritation in mice (Mus musculus). Clove leaf extract was prepared in cream preparations with a concentration of 10% and 11%. This test used a laboratory experimental method carried out at the Pharmacology Laboratory of the Yamasi Pharmacy Academy Makassar, then tested the irritating effect of Clove Leaf Extract Cream (Syzygium aromaticum L.) using the draize method on mice (Mus musculus) as test animals and observed for 24 hours,48 hours, 72 hours. Then observed the appearance of erythema and edema that occurred at each concentration of preparations in mice (Mus musculus). Based on the results of the study, it can be concluded that the ethanol extract cream of clove leaves (Syzygium aromaticum L.) at concentrations of 10% and 11% does not cause irritation.

EFEKTIFITAS LOTION EKSTRAK N-HEKSAN DAUN KLUWEK (Pangium edule Reinw) SEBAGAI PEMBASMI KUTU RAMBUT (Pediculus humanus capitis) SECARA INVITRO

Zakiah Thahir — 2024-02-10

Clove plant has been widespread in Indonesia, especially in the Makassar region. Clove plants contain cyanides (HCN) and compounds in plants that are toxic, including alkaloids, glycosides, proteins, alcohols, non-amino organic acids, tanins, phenols, resinoids, and terpenoids. Clove plants in addition to being a plant insecticide, clove seeds can be made material or cooking spices and also made oil fuel. This study aims to find out the effectiveness of the preparation of hair lotion extract n-hexan leaves kluwek (Pangium edule Reinw) as a deprivation of lice hair. This type of study is a laboratory experimental study using an in vitro method performed by observing the number of hair lice deaths in petri cups that each have been applied the preparation of hair lotion extract n-hexane leaves claw (concentration 5%, 10%, and 15%) compared with the control (-) base and control (+) peditox for 2 hours. The results of the study showed the preparation of hair lotion extract n-hexane leaf leaf with a concentration of 15% that most effectively destroyed lice with a leach death percentage of 100% equal to control (+) peditox that was able to destroy 10 lice in ± 20 minutes when compared with control (-) base could destroy as many as 9 lice in 1 hour 40 minutes.

PEMANFAATAN LIMBAH CANGKANG KERANG DARAH (Anadaragranosa) KOMBINASI EKSTRAK ETANOL DAUN SIRIH (Piper betle L.) DALAM BENTUK SEDIAAN PASTA GIGI

sukirawati sukirawati — 2024-02-10

Abstract
Toothpaste is a preparation intended for cleaning and shining the surface of teeht, preventing tooth decay, improving healthy gums, providing a healthy sensation in the mouth, and controlling mouth odor. Toothpaste can be made from blood cockle shell waste and betel leaf extract. Blood cockle shell contains high levels of calcium carbonate, while betel leaf contains high antioxidants. When combined, they can strengthen and whiten teeth. The objective of this research is to create a toothpaste preperation from blood cockle shell waste combined with ethanol extract of betel leaf that meets the quality standards based on SNI 12-3524-1995, including organoleptic tests ang pH tests. This research method is an experimental laboratory study. The results showed that the combination of blood cockle shell waste and ethanol extract of betel leaf can be made in to toothpaste that meets the physical quality test requirements based on SNI, including organoleptic tests, such as green color, distinctive smell of betel leaf extract, mint flavor, slightly rough texture, and average pH value of 7.

Abstrak
Pasta gigi adalah sediaan yang ditujukan untuk membersihkan dan mengkilaukan permukaan gigi, mencegah karies gigi, meningkatkan gusi yang sehat, memberikan sensasi sehat pada mulut dan mengontrol aroma mulut. Pasta gigi dapat dibuat dari limbah cangkang kerang darah dan ekstrak daun sirih. Cangkang kerang darah menandung kalsium karbonat yang tinggi sedangkan daun sirih mengandung antioksidan yang tinggi sehingga ketika dikombinasikan akan menguatkan gigi dan memutihkan gigi. Tujuan penelitian ini adalah untuk membuat sediaan pasta gigi dari limbah cangkang kerang darah kombinasi ekstrak etanol daun sirih yang memenuhi standar mutu fisik berdasarkan SNI 12-3524-1995 meliputi uji organoleptik dan uji pH. Metode penelitian ini bersifat eksperimental laboratorium. Hasil penelitian menunjukkan bahwa cangkang kerang darah kombinasi ekstrak etanol daun sirih dapat dibuat pasta gigi yang memenuhi syarat uji mutu fisik berdasarkan SNI meliputi uji organoleptik, yaitu warna hijau, bau khas ekstrak daun sirih, rasa mint, tekstur agak kasar dan uji pH rata-rata pH 7.

PEMBUATAN DAN UJI MUTU FISIK SEDIAAN BODY LOTION EKSTRAK KULIT BUAH RAMBUTAN (Nephelium lappaceum L) SEBAGAI ANTIOKSIDAN

yusriyani burhamin — 2024-02-12

Abstract. This study aims to determine the manufacture and physical quality test of the body lotion preparation of Rambutan skin extract (Nephelium lappaceum L). The research method used was experimental laboratory by conducting experiments to manufacture body lotion preparations and testing the physical quality of the preparation which was carried out at the Pharmaceutical Laboratory of the Yamasi Pharmacy Academy, Makassar. Rambutan Skin (Nephelium lappaceum L) were extracted by maceration for using ethanol as solvent. The made body lotion preparation with a concentration of 0,1% b/b and 1% b/b. Physical quality tests carried out were organoleptic test, homogeneity test, pH test, dispersion test and adhesion test. The results showed that Rambutanskin extract (Nephelium lappaceum L) with a concentration of 0,1% b/b and 1% b/b can be made into a body lotion preparation and the physical quality test requirements of good body lotion preparations.

PEMANFAATAN LIMBAH KULIT BUAH SALAK PONDOH (Salaccae edulis Reinw) MENJADI SEDIAAN SAMPO DAN AKTIVITASNYA TERHADAP Staphylococcus epidermidis DAN Candida albicans

Yuyun Sri Wahyuni — 2024-02-16

In South Sulawesi Province, the pondoh salak plant is widely used as medicine. Many people only eat the fruit and throw away the skin, because they consider the skin of the Pondoh salak fruit to be useless. Pondoh salak fruit skin contains flavonoids, saponins, tannins, phenols, terpenoids and alkaloids. The saponin content functions as a foam maker and flavonoids function to accelerate hair growth. This research aims to make a shampoo preparation from the ethanol extract of Pondoh salak fruit peel (Salacca edulis Reinw) and test the stability of the shampoo and test the activity of the shampoo preparation of Pondoh salak fruit peel ethanol extract (Salacca edulis Reinw) on the growth of Staphylococcus epidermidis and Candida albicans. This research used laboratory experimental methods, formulating shampoo from ethanol extract of pondoh salak fruit peel (Salacca edulis Reinw) into four formulations with respective concentrations, namely F0: 0%, F1: 10%, F2: 15% and F3: 20%. The physical stability test of the ethanol extract shampoo preparation of pondoh salak fruit peel (Salacca edulis Reinw) includes organoleptic test, homogeneity test, pH test, foam power test, viscosity test, free alkali test and storage stability test. Free alkali test results show that all formulations contain alkali. Storage stability test results for 6 cycles or 12 days at temperature 4^OC and 40^OC all dosage formulations remain stable. The results of the organoleptic test and homogeneity test remained stable, for the pH test and foam power there was a decrease and for the viscosity test there was an increase after the cycling test was carried out but it still met SNI requirements. Meanwhile, in testing the activity of Staphylococcus epidermidis in F1 10% the resulting inhibitory zone area was an average of 32.93 mm, in F2 15% the resulting inhibitory zone area was 28.56 mm, and in F3 20% the resulting inhibitory zone area was 20.93mm. Meanwhile, in the Candida albicans test, F1 10% inhibitory zone area averaged 24.61 mm, F2 15% average inhibitory zone area 25.94 mm, F3 inhibitory zone area 19.44 mm. Based on the results of the research that has been carried out, it can be concluded that the ethanol extract of pondoh salak fruit peel (Salacca edulis Reinw) meets the requirements of the physical stability test and can inhibit the growth of Staphylococcus epidermidis. The three inhibitory power measurements of each formulation are categorized as having a very strong inhibition zone area, while the activity testing for Candida Albicans F1 and F2 has a very strong zone of inhibition. very strong inhibition while F3 has a strong inhibition zone.

TINGKAT PENGETAHUAN ORANG TUA TERHADAP PENGGUNAAN ANTIBIOTIKA PADA ANAK

Suhartini tansri — 2024-02-16

Antibiotics used for the treatment of infections. The irrational use of antibiotics can result in a significant increase in antibiotic resistance, especially infectious diseases. This study was conducted to determine the level of knowledge of antibiotic use for children in the community of Taipajawaya Hamlet, Barembeng Village, Gowa Regency. This study is an observational study with a survey method research design or quantitative method using a questionnaire. The results of the study obtained the largest correct answer = 96% which stated that the community mostly knew that information on how to use antibiotic drugs should be conveyed when handing over drugs. And the smallest number of correct answers = 63% which states that the community is less aware that all antibiotic drugs must be taken until they run out even though they feel cured. The level of knowledge of the people of Taipajawaya Hamlet, Barembeng Village, Gowa Regency towards the use of antibiotics in the sufficient category (73.6%) as many as 67 out of 91 people.

TINGKAT PENGETAHUAN MASYARAKAT TENTANG PENGGUNAAN OBAT ANTI HIPERTENSI DI PUSKESMAS MONCOBALANG KABUPATEN GOWA TAHUN 2022

Zulfahmi Hamka — 2024-02-16

Hypertension is a chronic disease characterized by blood pressure that tends to rise and fall as a result of which long treatment is needed even for life. This research was conducted with a descriptive method. Respondents in this study were patients who visited the Moncobalang Public Health Center during the study. Sampling was obtained by purposive sampling technique, namely sampling only on individuals based on certain considerations and characteristics. Respondents in this study were 92 people as respondents. The level of patient knowledge includes six dimensions, namely knowledge, understanding, application, analysis, synthesis and assessment. The data obtained showed that the level of public knowledge about the use of antihypertensive drugs with a percentage of 64.68% in the Good category.