Jurnal Kesehatan Yamasi Makassar

PEMBUATAN DAN UJI MUTU SEDIAAN GEL HAND SANITIZER EKSTRAK ETANOL DAUN MATOA (Pometia pinnata J.R & G. FORST)

Arief Azis — 2025-01-30

Matoa leaves contain phytochemical compounds, in the form of secondary metabolite compounds such as flavonoids, alkaloids, tannins, saponins, terpenoids and coumarins. Secondary metabolite compounds are defined as antioxidant compounds whose role is to ward off free radicals. This research aims to determine the manufacture and physical quality testing of hand sanitizer gel preparations from matoa leaf extract (Pometia pinnata J.R & G. FORST). The research method used was experimental laboratory by conducting experiments for making hand sanitizer gel preparations and physical quality tests on the preparations carried out in the teaching factory laboratory of the Yamasi Pharmacy Academy, Makassar. Matoa leaves (Pometia pinnata J.R & G. FORST) were extracted by maceration for 1×24 hours using 96% ethanol solvent. Hand sanitizer gel preparations were made in negative control and 3 concentration formulas of 2%, 3% and 4%. The physical quality tests carried out are organoleptic test, homogeneity test, PH test, spreadability test. The research results stated that matoa leaf extract (Pometia pinnata J.R & G. FORST) could be made into hand sanitizer gel preparations with concentrations of 2%, 3% and 4%, and met the requirements for good physical quality tests and irritation tests for hand sanitizer gel preparations.

UJI DAYA HAMBAT SEDIAAN SABUN CAIR PEMBERSIH KEWANITAAN EKSTRAK KENTAL BIJI PINANG (Areca catechu L.) TERHADAP Candida albicans

dzulasfi — 2025-01-30

Tujuan dari penelitian ini adalah untuk mengetahui daya hambat sabun cair pembersih kewanitaan ekstrak kental biji pinang (Areca catechu L.) terhadap Candida albicans. Metode yang digunakan dalam penelitian ini adalah eksperimen laboratorium untuk menguji daya hambat sediaan sabun cair pembersih kewanitaan pada jamur Candida albicans. Dari hasil penelitian daya hambat sabun cair pembersih kewanitaan ekstrak kental biji pinang dengan konsentrasi 1% menghasilkan rata rata zona hambatan sebesar 9,04 mm, konsentrasi 2% didapatkan zona hambatan 9,25 mm, konsentrasi 3% didapatkan zona hambatan 9,32 mm, kontrol positif 12.07mm dan kontrol negatif 0 mm.

UJI EFEKTIVITAS SEDIAAN HAND SANITIZER EKSTRAK DAUN KEMANGI (Ocimum sanctum.L) TERHADAP Staphylococcus aureusThis study aims to determine whether the hand sanitizer preparation of basil leaf extract (Ocimum sanctum.L) has an antibacterial effect against S

taufiq taufiq — 2025-01-30

This study aims to determine whether the hand sanitizer preparation of basil leaf extract (Ocimum sanctum.L) has an antibacterial effect against Staphylococcus aureus at concentrations of 1%, 2% and 4%. Basil leaf extract is made in hand sanitizer preparations with concentrations of 1%, 2% and 4%. This test used experimental methods in the Microbiology Laboratory of the Yamasi Pharmaceutical Academy, then tested the antibacterial effectiveness of the basil leaf extract hand sanitizer preparation (Ocimum Sanctum.L) . Then observations were made by measuring the zone of inhibition that existed at each concentration of the preparation for the test bacteria Staphylococcus aureus. The results obtained showed that the inhibition zone of 1% concentration had a diameter of 2.88 mm, 2% concentration had a diameter of 3.44 mm, and 4% concentration had a diameter of 5.14 mm. With the results of inhibiting bacterial growth which are categorized (weak < 5 mm, medium 5-10 mm). The conclusion of this study states that the hand sanitizer preparation of basil leaf extract (Ocimu sanctum.L) with a concentration of 4% is better than concentrations of 2% and 1%.

Formulation and Production of Eco-Enzyme Herbal Bath Soap as a Natural Antiseptic

Muhammad Tahir — 2025-01-30

This study aimed to develop herbal bath soap formulations based on eco enzyme and evaluate their physical characteristics according to SNI quality standards. The soap was formulated using the Cold Process method with three formula variations: F0, F1, and F2. The pH test results showed that all formulas were within the range of 9.03–9.05, meeting the SNI standard. The moisture content test showed the lowest value in F0 and the highest in F2, all of which were within the SNI standard. The total fat of the formulas ranged from 45.005% to 52.815%, meeting the maximum limit of the SNI. The free alkali values of all formulas ranged from 0.0095% to 0.0949%, in accordance with the SNI standard. Formula F2 was considered the best formulation because it produced soap with optimal physical characteristics and met all standard parameters. Eco enzyme has been proven effective as an active ingredient with potential antifungal, antibacterial, and natural cleansing properties in herbal bath soap formulations.

PEMBUATAN DAN UJI MUTU FISIK SEDIAAN SALEP KULIT DARI EKSTRAK BIJI KAKAO (Theobroma cacao L.)

Rusmin Rusmin — 2025-02-05

Abstract. This research aims to make a preparation of cocoa bean extract (Theobroma cacao L.) skin ointment that meets the requirements for a good physical quality test for skin ointment using vaseline album and adeps lanae ointment bases. Cocoa beans (Theobroma cacao L.) were extracted using the maceration method using 96% ethanol then the extraction results were made into 3 skin ointment preparations with the same base and using cocoa bean extract (Theobroma cacao L.) with a concentration of 5% b/b, 10 % b/b, and 15% b/b. The research results show that skin ointment preparations with extract concentrations of 5% b/b, 10% b/b, and 15% b/b can meet the physical quality test parameters including organoletic tests which produce a semi-solid form, distinctive odor, brown color, test homogeneity obtained homogeneous results, the pH test obtained a pH of 5 which met the skin pH requirements of 4.5 – 6.5, the spreadability test obtained results for a concentration of 5% b/b resulting in a spreadability of 5.2 cm, a concentration of 10% b/b b produced 5.6 cm, and a concentration of 15% b/b produced 6.5 cm, where this result met the standard requirements for good ointment spreadability in the range of 5 - 7 cm, and the adhesive test produced 20 - 37 seconds. Where this result meets the adhesion requirement, namely more than 4 seconds.

PEMBUATAN DAN UJI MUTU FISIK SEDIAAN DEODORAN SPRAY DARI EKSTRAK PELEPAH SEREH (Cymbopogon nardus L.)

Agust Dwi Djajanti Djajanti — 2025-02-05

This study aims to determine the preparation and physical quality test of deodorant spray preparation from lemongrass frond extract (Cymbopogon nardus L.) The research method used is laboratory experimental. First the simplisia was extracted by maceration method for 2 x 24 hours using 96% ethanol solvent. The results of the thick extract were made deodorant spray preparations in the form of 4 formulas F1 27%, F2 28% and F3 29% with a deodorant spray base consisting of 96% ethanol, propylenglicol and distilled water. Physical quality tests carried out are organoleptic test, pH test, homogeneity test and dry time test. The results of the organoleptic test F0, F1, F2, F3 have a liquid form, distinctive odor and orange color while for F0 has a liquid form, odorless and clear color. The results of the pH test F0, F1, F2, F3 all preparations have met the requirements with a pH parameter value of 3 - 7.5. The homogeneity test results of all preparations have met the requirements. The dry time test has met the requirements with a drying time of < 5 minutes in the deodorant spray preparation. From the results of the study stated that lemongrass frond extract (Cymbopogon nardus L.) can be made in the form of deodorant spray preparations with a concentration of F0 base, F1 27%, F2 28%, F3 29% have met the quality requirements based on SNI 16-4951-1998.

TINJAUAN EFEK SAMPING PENGGUNAAN METFORMIN PADA PASIEN DIABETES MELITUS TIPE II DI APOTEK KIMIA FARMA ALAUDDIN BULAN JULI-DESEMBER 2023

sukirawati sukirawati — 2025-02-05

Diabetes Melitus tipe II adalah penyakit dengan suatu kondisi yang mempengaruhi cara tubuh memproses gula darah. Pengobatan lini pertama penderita DM tipe II menggunakan metformin. Namun disamping itu, metformin dapat menimbulkan beberapa efek samping yang tidak diinginkan. Tujuan penelitian ini adalah untuk mengetahui efek samping dari penggunaan Metformin pada penderita DM tipe II. Jenis penelitian yang digunakan bersifat deskriptif yang pengumpulan datanya secara retrospektif. Berdasarkan hasil penelitian yang telah dilakukan dapat diketahui penderita DM tipe II yang paling banyak mengalami efek samping di Apotek Kimia Farma Alauddin Makassar yakni pada usia 60 tahun ke atasdengan efek samping terbanyak adalah defisiensi vit. B12 dengan persentase 10,88%. Berdasarkan dosis obat harian penggunaan metformin diketahui banyak dikonsumsi yang menimbulkan efek samping yakni 2 x 500 mg (48%).

Karakterisasi Mutu Fisik Teh Celup Kulit Buah Kopi Arabika (Coffea arabica L)

Nurul Hidayah Base — 2025-02-05

Kulit buah kopi arabika (Coffea arabica L.) merupakan bagian terluar dari buah kopi yang mengandung senyawa polifenol yang dapat menangkal radikal bebas dan memiliki aktivitas antioksidan yang tinggi, namun belum dimanfaatkan secara maksimal oleh masyarakat. Penelitian ini bertujuan untuk mengetahui apakah kulit buah kopi arabika dapat dibuat dalam sediaan teh celup herbal dan mengetahui karakterisasi mutu fisiknya berdasarkan keadaan air seduhan, pH, kadar air dan kadar ekstrak dalam air. Metode penelitian yang digunakan adalah eksperimental laboratorium dengan melakukan pembuatan teh celup herbal kulit buah kopi arabika yang selanjutnya dilakukan karaketrisasi mutu fisik dengan mengacu pada SNI (3836 : 2013). Hasil pengujian karakteristik mutu fisik teh celup herbal kulit buah kopi arabika menunjukkan bahwa keadaan air seduhan berwarna merah kecoklatan, berbau khas aromatik dan tidak berasa. pH sebesar 4 (persyaratan pH 3,7-6,1), kadar air sebesar 7,7 % (< 8%), dan kadar ekstrak dalam air sebesar 36 % (> 32 %). Sehingga dapat disimpulkan bahwa kulit buah kopi arabika dapat dibuat menjadi teh celup herbal dengan karakterisasi mutu fisik yang sesuai dengan syarat mutu fisik teh kering dalam kemasan.

UJI DAYA HAMBAT SEDIAAN TONER WAJAH INFUSA DAUN BELIMBING WULUH (Averrhoa bilimbi L.) TERHADAP Propionibacterium acnes

yusriyani burhamin — 2025-02-06

. This research has been made with the objective to determine at what concentration the infusa of bilimbi leaves (Averrhoa bilimbi L.) in the form of facial toner preparations can inhibit Propionibacterium acnes bacteria optimally. The method used in this research is a laboratory experimental method by testing the inhibition of toner preparations. Belimbing wuluh leaves were extracted using the infusa method then made facial toner preparations with concentrations of 10%, 20% and 30% and tested with the paperdisk method. From the results of the research on the inhibition of facial toner preparations of infusa extract of bilimbi leaves (Averrhoa bilimbi L.) showed that at concentrations of 10% and 20% could not inhibit the growth of Propionibacterium acnes bacteria. Meanwhile, the 30% concentration can inhibit the growth of Propionibacterium acnes bacteria optimally optimally with the inhibition zone around the paperdisk.