Jurnal Kesehatan Yamasi Makassar

ANALISIS FAKTOR RESIKO KEJADIAN TUBERCULOSIS DI WILAYAH PUSKESMAS SYAMTALIRA BAYU

2025-08-06T14:10:58+08:00

World Health Organization (WHO) menyatakan Tuberkullosis (TB) sebagai masalah kesehatan masyarakat yang sangat penting dan serius diseluruh dunia dan merupakan penyakit yang menimbulkan kedaruratan global (Global Emergency) karena di sebagian besar negara di dunia penyakit TB paru tidak terkendali, Hal ini disebabkan oleh banyaknya penderita yang tidak berhasil disembuhkan, serta merupakan penyebab utama kematian yang disebabkan oleh penyakit infeksi Penelitian ini merupakan penelitian kasus kontrol yang bertujuan untuk menganalisis hubungan antara diabetes melitus (DM) dengan kejadian tuberkulosis (TB) pada seluruh pasien TB di wilayah kerja Puskesmas Syamtalira Bayu. Variabel data mengenai riwayat penyakit DM, usia, jenis kelamin, pekerjaan, kontak dengan pasien TB dan riwayat vaksin BCGA. Analisis data pada Tabel 1 menunjukkan profil pasien TB paru yang didominasi oleh lansia dengan usia di atas 49 tahun (63,16%) dan perempuan (73,68%). Pekerjaan sebagai ibu rumah tangga merupakan pekerjaan yang paling banyak dilakukan oleh responden (8 orang), diikuti oleh pelajar/mahasiswa, wiraswasta, dan tidak bekerja. Kondisi komorbiditas diabetes melitus juga cukup signifikan, dengan 63,16% responden memiliki riwayat penyakit ini. Menariknya, meskipun TB sering dikaitkan dengan kontak langsung dengan pasien, mayoritas responden (73,68%) tidak memiliki riwayat kontak langsung dengan pasien TB sebelumnya. Selain itu, semua responden tidak memiliki riwayat vaksinasi BCG. Kesimpulan dari laporan ini menunjukkan bahwa tuberkulosis (TB) masih menjadi masalah kesehatan yang signifikan, terutama di kalangan lansia yang memiliki faktor risiko seperti diabetes melitus (DM). Penelitian ini mengungkapkan bahwa individu berusia di atas 49 tahun dengan DM memiliki kemungkinan yang lebih tinggi untuk mengalami kejadian TB.

UJI AKTIVITAS FRAKSI N-HEKSAN, ETIL ASETAT, ETANOL DAUN PARE (Momordica charantia L.) TERHADAP Staphylococcus epidermidis DAN Salmonella thypi

2025-08-06T14:10:39+08:00

Bitter melon leaves (Momordica charantia L.) contain compounds such as flavonoids, saponins, triterpenoids, glycosides and alkaloids. This study aims to determine the difference in antibacterial activity of the N-hexane, Ethyl acetate and Ethanol 96% fractions fram bitter melon leaves (Momordica charantia L.) against the bacteria Staphylococcus epidermidis and Salmonella thypi. The research method is an experimental study to see the antibacterial activity of the N-hexane, ethyl acetate and etanol 96% fractions at concentrations of 5%, 10% and 15% using the disc diffusion method. The results of the research showed that Staphylococcus epidermidis bacteria obtained an inhibitory power of 5% (5,95 mm), 10% (12,23 mm), 15% (14,05 mm) for the N-hexane fraction. Ethyl acetate fraction 5% (6,08 mm), 10% (7,37 mm), 15% (10,93 mm). Ethanol fraction of 5% (6,37 mm), 10% (12,8 mm), 15% (13,98 mm). Salmonella thypi bacteria against the N-hexane fraction obtained an inhibitory power of 5% (7,83 mm), 10% (12,47 mm), 15% (13,88 mm). The ethyl acetate fraction is 5% (5,43 mm), 10% (10,85 mm), 15% (13,88 mm). Ethanol fraction of 5% (7,77 mm), 10% (10,27 mm), 15% (15,5 mm). It can be concluded that the N-hexane, ethyl acetate and ethanol 96% fractions have antibacterial activity.

AKTIVITAS TABIR SURYA EKSTRAK ETANOL DAUN Acacia auriculiformis ASAL KOLAKA MENGGUNAKAN SPEKTROFOMETRI UV-Vis

2025-08-06T14:11:17+08:00

Excessive exposure to UV radiation can cause skin damage. Preventive measures can be taken by using sunscreen. Acacia auriculiformis is a species from the Fabaceae family, many of which are known for their antioxidant activity. Acacia auriculiformis can act as a natural sunscreen because it contains secondary metabolite compounds with conjugated double bond structures, which are known to reduce the intensity of UV exposure on the skin by absorbing ultraviolet radiation. This study aimed to identify the secondary metabolites in the ethanol extract of Acacia auriculiformis leaves from Kolaka and to determine its Sun Protection Factor (SPF) value using UV-Vis spectrophotometry. The extraction of Acacia auriculiformis leaves was carried out using the maceration method with 70% ethanol as the solvent. The sunscreen activity was determined based on the SPF values. The SPF values of the extract at concentrations of 50 ppm, 100 ppm, 150 ppm, and 200 ppm were 3.8712 (minimal protection), 6.4880 (extra protection), 9.5359 (maximum protection), and 12.5816 (maximum protection), respectively. The results indicate that sunscreen activity increases in proportion to the extract concentration. Acacia auriculiformis leaves have the potential to be developed as a sunscreen formulation.

PEMBUATAN DAN UJI DAYA HAMBAT SEDIAAN SERUM WAJAH EKSTRAK DAUN PEPAYA (Carica papaya L.) TERHADAP staphylococcus epidermidis

2025-08-06T14:10:21+08:00

This study aims to determine the inhibitory power of facial serum preparations from papaya leaf extract (Carica papaya L.) on the growth of Staphylococcus epidermidis. The research method carried out was experimental laboratory research, to determine the inhibitory power of facial serum from papaya leaf extract (Carica papaya L.) on the growth of Staphylococcus epidermidis which was carried out at the Microbiology Laboratory of the Yamasi Pharmacy Academy, Makassar. Papaya leaves were extracted using the maceration method using 96% ethanol solvent, the extract obtained was then made into a facial serum preparation with a concentration of 6% (F1), 8% (F2), 10% (F3) and as a serum base (F4). The research results stated that facial serum preparations of papaya leaf extract (Carica papaya L.) could inhibit the growth of Staphylococcus epidermidis with concentrations of 6%, 8%, and 10%.

UJI AKTIVITAS SABUN MANDI HERBAL ECOENZYME SEBAGAI ANTISEPTIK ALAMI TERHADAP Staphylococcus aureus DAN Propionibacterium acne

2025-08-06T14:10:03+08:00

Evaluation of the Antiseptic Activity of Herbal Bath Soap Containing Eco Enzyme Against Staphylococcus aureus and Propionibacterium acnes. Herbal bath soap is a skin cleanser formulated with a soap base and permitted additives to enhance its functionality and consumer appeal. The use of natural ingredients, particularly fruit and vegetable waste, offers a sustainable source of active compounds. Through fermentation, these materials can be converted into eco enzyme, which contains various bioactive substances with potential antibacterial properties. This study aimed to assess the antibacterial activity of herbal bath soap formulated with eco enzyme against Staphylococcus aureus and Propionibacterium acnes. The inhibition zone assay demonstrated that soap containing 25% and 50% eco enzyme exhibited average inhibition zones of 1.596 mm and 1.69 mm against P. acnes, respectively, while the negative control produced a zone of 0.88 mm. For S. aureus, the inhibition zones at the same concentrations were 3.44 mm and 1.997 mm. These findings suggest that eco enzyme-based herbal bath soap exhibits antibacterial effects against both tested bacterial strains. However, the observed inhibition remains within the weak category (<5 mm), indicating a limited but measurable antibacterial potential.

UJI EFEKTIVITAS GEL EKSTRAK DAUN MELINJO (Gnetum gnemon L.) TERHADAP Staphylococcus epidermidis

2025-08-06T14:09:42+08:00

Penelitian ini bertujuan Untuk mengetahui efektivitas sediaan gel ekstrak daun melinjo (Gnetum gnemon L.) dalam menghambat pertumbuhan bakteri Staphylococcus epidermidis dan konsentrasi optimum sediaan gel ekstrak daun melinjo dalam menghambat pertumbuhan Staphylococcus epidermidis. Daun melinjo diekstraksi menggunakan metode maserasi dengan etanol 96% dan diformulasikan menjadi sediaan gel konsentrasi 1%, 2%, dan 3%. Uji aktivitas antibakteri dilakukan dengan metode paperdisk pada media Nutrient Agar (NA) yang telah diinokulasi bakteri uji, serta menggunakan klindamisin sebagai kontrol positif dan basis gel sebagai kontrol negatif. Hasil menunjukkan bahwa gel ekstrak daun melinjo efektif dalam menghambat pertumbuhan Staphylococcus epidermidis. Dan konsentrasi optimum dari gel ekstrak daun melinjo yang dapat menghambat pertumbuhan Staphylococcus epidermidis adalah konsentrasi 3% dengan rata-rata diameter zona hambat 14,43 mm dengan kategori kuat.

UJI DAYA HAMBAT EKSTRAK KULIT DAGING BUAH LONTAR (Borassus flabellifer L.) TERHADAP PERTUMBUHAN Staphylococcus aureus

2025-08-06T14:09:24+08:00

Kulit daging buah lontar (Borassus flabellifer L) memiliki banyak kandungan Flavonoid, tanin, dan saponin yang merupakan kandungan kimia yang berkhasiat sebagai pengobatan. Penelitian ini bertujuan untuk mengetahui aktivitas ekstrak kulit daging buah lontar (Borassus flabellifer L.) terhadap Staphyloccous aureus dan menentukan konsentrasi optimal ekstrak kulit daging buah lontar Staphylococcus aureus. kulit daging buah lontar (Borassus flabellifer L.) Dibuat dalam sediaan ekstrak dengan konsentrasi 5%, 10%, 15% pengujian ini menggunakan metode eksperimental kemudian dilakukan pengujian daya hambat ekstrak kulit daging buah lontar (Borassus flabellifer L.) dengan menggunakan variasi konsentrasi 5%, 10%, 15% serta kontrol negatif menggunakan DMSO menggunakan metode paper disk dan medium agar ( NA) sebagai media dan di inkubasi selama 1 x 24 jam. Hasil penelitian menunjukkan bahwa ekstrak kulit daging buah lontar (Borassus flabellifer L.) memiliki daya hambat terhadap pertumbuhan bakteri Staphylococcus aureus. Ekstrak yang digunakan dalam tiga konsentrasi, yaitu 5%, 10%, dan 15%, menunjukkan total diameter zona hambat masing-masing sebesar 44,6 mm, 45,3 mm, dan 52 mm, dengan rata-rata zona hambat sebesar 14,8 mm, 15,1 mm, dan 17,3 mm. Seluruh hasil tersebut termasuk dalam kategori daya hambat kuat.

DISTRIBUSI PENGGUNAAN BERAGAM JENIS VAKSIN COVID-19 DI WILAYAH KERJA PUSKESMAS GENTUNGAN, DESA GENTUNGAN, KECAMATAN BAJENG BARAT, KABUPATEN GOWA TAHUN 2022

2025-08-06T14:09:05+08:00

In December 2019, Wuhan City in Hubei Province, China, became the epicenter of a novel coronavirus outbreak, later identified as SARS-CoV-2, the causative agent of COVID-19. Common symptoms of COVID-19 infection include fever, cough, and shortness of breath. This study aimed to determine the percentage distribution of various COVID-19 vaccine types administered at the Gentungan Public Health Center. Employing a non-experimental, descriptive approach, this research analyzed existing data without intervention on test subjects, utilizing a retrospective data collection method. The study population comprised 9,000 individuals, from which a sample of 383 participants was selected. The results indicated the following distribution of vaccine usage: Sinovac was administered to 236 individuals (61.61%), Pfizer to 61 individuals (15.92%), Moderna to 53 individuals (13.83%), and AstraZeneca to 33 individuals (8.61%). Sinovac was the most frequently administered vaccine, likely due to its ample availability and the lack of choice afforded to the public regarding vaccine selection.

PENGARUH PERBEDAAN KONSENTRASI EMULGATOR PADA SEDIAAN LOTION EKSTRAK DAUN BIDARA (Ziziphus spina-christi L.) TERHADAP MUTU FISIK

2025-08-06T14:08:46+08:00

Bidara leaves contain many useful ingredients, including alkaloids, phenols, flavonoids, saponins, quercetin, and terpenoids and the leaves have the potential to act as natural antioxidants.To increase the utilization or use value of bidara leaves they can be mae into a preparation, namely lotion. The aim of this research is to make and test the quality of a physicalpreparation of lotion from bidara leaf extract (Ziziphus spina-christi L.). Bidara leaves were extracted using a maceration method using 96% ethanol solvent for 3x24 hours. This lotion preparation is made with varying concentrations of Anionic and Nonionic emulsifiers and then a physical evaluation is carried out including organoleptic tests, homogeneity tests, pH tests of the preparations, adhesion tests and spreadability tests. Based on the results of the research carried out, it can be concluded that differences in emulsifier concentration affect quality including organoleptics, adhesion, dispersion and pH. The results of the physical evaluation of lotion preparations in the organoleptic test were that F1 was brown, F2 was green, had a distinctive aroma, F1 preparation was thick, F2 was slightly thick and both textures were smooth. The lotion preparation was mixed homogeneously, the pH and adhesion tests met the standard requirements but the spreadability test did not meet the standard requirements.

ANALISIS TINGKAT KEPUASAN PASIEN TERHADAP PELAYANAN KEFARMASIAN DI APOTEK TASIKMADU KARANGANYAR

2025-08-06T14:08:26+08:00

Patient satisfaction is an important and crucial indicator of service quality and pharmacy performance. Therefore, pharmacies must be oriented towards patient satisfaction and patient safety in every service provided. Continuous improvement needs to be done in order to maintain service quality. Periodic and continuous evaluation is a must carried out by pharmacies. The purpose of this study was to determine the performance of pharmacies in their pharmaceutical services to patients. This research design is descriptive quantitative with observational methods through prospective studies. The population and sample were customers who had experienced the services of Tasikmadu Pharmacy from February - March 2025 by giving questionnaires to 100 patients of Tasikmadu Pharmacy. Measurement of satisfaction based on servqual dimensions, namely assurance, empathy, responsiveness, physical facilities (tangible), and reliability. Data analysis using Likert scale. Based on the results of the analysis, the level of satisfaction with services in the guarantee dimension at Tasikmadu Pharmacy is very satisfied with a score of 90.91%, the empathy dimension is very satisfied (90.5%), the responsiveness dimension (89.5%), the physical facilities dimension (88.43%), and the reliability dimension (87.17%). The achievement of a satisfaction score of 89.30% in the five dimensions of service indicates that the services at the Tasikmadu Pharmacy are considered very satisfying by patients. However, it is necessary for pharmacies to continue to strive to improve their performance in providing services to patients, especially in the reliability dimension.

EVALUASI MUTU FISIK DAN UJI IRITASI KOSMETIKA LULUR DENGAN MEMANFAATKAN BONGGOL NANAS SEBAGAI BAHAN AKTIF

2025-08-06T14:06:31+08:00

The pineapple variety used in this research was queen pineapple. Pineapple processing produces waste in the form of pineapple tubers. The aim of this research is to make cosmetic scrubs with the active ingredient queen variety pineapple weevil (Ananas cosmosus L) and to determine the results of physical quality tests and determine the safety/irritation of body scrub preparations from pineapple weevils. This scrub preparation is made with three formulas using different concentrations of pineapple weevil powder, namely 5%, 7% and 9%. Physical quality tests of scrub preparations include organoleptic tests, homogeneity tests, pH tests and spreadability tests. Based on the results of the physical quality test, it shows that the formula with a pineapple weevil active substance concentration of 5% and the formula with a pineapple weevil active substance concentration of 7% is a formula that meets the physical quality test standards. Irritation/safety tests were carried out on rabbits and showed that the scrub preparation did not cause irritation, the degree index produced for all preparations tested was 0 (no irritation)

PENGUJIAN AKTIVITAS SIRUP EKSTRAK BIJI DAN KULIT BUAH PEPAYA (Carica papaya L.) TERHADAP PERTUMBUHAN Escherichia coli

2025-08-06T14:08:08+08:00

This study aims to determine the antibacterial activity and the inhibition zone category of papaya (Carica papaya L.) seed and peel extract syrup against the growth of Escherichia coli. Papaya seed and peel extracts were formulated into syrup preparations with concentrations of 5% and 15%. Testing was carried out experimentally at the Microbiology Laboratory of the Yamasi Makassar Pharmacy Academy using the paper disk method on Nutrient Agar (NA) media, then incubated for 24 hours at 37°C. The measurement results showed that the inhibition zone in papaya seed extract syrup was 8.9 mm at a concentration of 5% and 10.28 mm at a concentration of 15%, which was categorized as moderate (6–10 mm). Meanwhile, papaya peel extract syrup produced an inhibition zone of 11.65 mm at a concentration of 5% and 13.45 mm at a concentration of 15%, classified as strong (11–20 mm). In conclusion, papaya seed and peel extract syrup with a concentration of 15% has a higher effectiveness in inhibiting the growth of Escherichia coli compared to a concentration of 5%.

FORMULASI DAN UJI MUTU FISIK GRANUL EFFERVESCENT DARI TEMULAWAK (Curcuma xanthorrhiza Roxb)

2025-08-06T14:07:48+08:00

Abstract. Curcuma (Curcuma xanthorrhiza Roxb) is a leading Indonesian medicinal plant that needs to be developed and utilized. Temu buffoonery contains various chemical compounds, starch is one of the most abundant ingredients found in the temu buffoonery plant. This research aims to formulate Curcuma (Curcuma xantoriza Roxb) rhizome, citric acid, tartaric acid, sodium bicarbonate, lactose, 70% alcohol and to test the physical quality of the preparation which includes organoleptic test, flow time test, soluble time test, water content test. , and the pH test resulted that the effervescent granule preparation met the physical quality requirements as a good effervescent preparation. Based on the research results, the best formula concentration data was obtained in each physical quality test of the preparation, namely formula III with a binder concentration of 6% (P <0.05), with an average flow time (9.20 seconds), dissolution time (3.46 minutes) , moisture content (0.54%), pH (6.86). This reaffirms that the research has successfully developed a granular effervescent formulation from Curcuma (Curcuma xanthorrhiza Roxb) that meets physical quality standards, especially in Formula III with a 6% binding concentration. This achievement opens up opportunities for a broader utilization of traditional Indonesian medicinal plants in a more modern and effective form. Furthermore, this finding also emphasizes the need for further research, which can focus on exploring the bioactive potential of Curcuma and further formulation innovation.

PEMBUATAN DAN UJI MUTU FISIK SEDIAAN BODY LOTION PATI BENGKUANG (Pachyrhizus erosus L.).

2025-08-06T14:07:28+08:00

Body lotion is a skin moisturizing cosmetic that is included in the emollient (softener) group, has moisturizing properties and is easy to apply to the skin. Body lotion can be made from plants, one of which is yam tubers. A study has been conducted with the aim of making and testing the physical quality of yam starch body lotion preparations (Pachyrhizus erosus L.). This research method was carried out using experimental research, namely making body lotion preparations from yam starch (Pachyrhizus erosus L.). Body lotion preparations from yam starch (Pachyrhizus erosus L.) were made with variations in concentration F0 (base), F1 3%, F2 5%, F3 7%. Evaluation of body lotion preparations includes organoleptic tests, homogeneity tests, pH tests, and spreadability tests. The results of the study showed that yam starch can be made into body lotion preparations that meet physical quality including organoleptic tests, namely white in color, distinctive aroma, slightly thick in shape and soft in texture. The body lotion preparation was mixed homogeneously and had an average pH value of 6, and an average spread of 6.4 cm.

POTENSI EKSTRAK ETANOL DAUN SUKUN (Artocarpus altilis) SEBAGAI BAHAN TABIR SURYA DENGAN PENENTUAN NILAI Sun Protection Factor (SPF) SECARA In Vitro

2025-08-06T14:07:09+08:00

This study aims to determine the value of Sun Protection Factor (SPF) In Vitro Leaf Extract Ethanol Breadfruit (Artocarpus altilis) as a Material Sunscreen. The study design was an observational laboratory that carried out in the Laboratory Farmakognosi-fitokimia Study Pharmacy Faculty of Medicine and Health, Muhammadiyah University. In a study determining the SPF in vitro is done by making a solution of ethanol extract of leaves of breadfruit with a concentration of 25 ppm, 50 ppm, 100 ppm and 200 ppm were then the absorbance is measured using a UV-Vis spectrophotometer at a wavelength of 290-320 nm at intervals of 5 nm. The results showed that the ethanol extract of leaves of breadfruit at a concentration of 25 ppm by 1600, 50 ppm at 2.5966, 6.9166 at 100 ppm, and 200 ppm of 50.6811. Based on the results of this study concluded that the ethanol extract of leaves of breadfruit can be used as a sunscreen active ingredient in concentrations above 50 ppm (SPF value> 2).

UJI EFEKTIVITAS EKSTRAK ETANOL BUAH BINTARO (Cerbera odollam Gaerthn) TERHADAP PENURUNAN GLUKOSA DARAH PADA TIKUS PUTIH (Rattus norvegicus)

2025-08-06T14:06:51+08:00

This study aims to determine the efectivity of Bintaro Fruit (Cerbera odollam gaerthn) Ethanol Extract Against Blood Glucose Decrease in White Rats (Rattus Norvegicus. The research design used was an experimental laboratory carried out in the pharmacology laboratory of the Department of Pharmacy, Pancasakti University. This study used 15 rats. male white rats were divided into 5 groups consisting of group I as a negative control by giving 1% w/v Na.CMC suspension, groups II, III, IV as a treatment group given Bintaro Fruit extract 1% w/v, 3% w/v, 5% w/v And group V was given Glibenclamide suspension as a positive control.The results showed that the percentage reduction in blood glucose for negative control, treatment and positive groups was 11.37%, 32.03%, 65, respectively. 46%, 86.15%, 95.5% The most effective concentration was 5% w/v concentration with an average value of 86.15% reduction, but it has not been able to match the effectiveness of Glibenclamide. in statistical testing using the Graphad Prims program for an alpha rate of 0.05, P value of 0.0001 is significant, the F value is 608.3.

PEMBUATAN DAN UJI MUTU FISIK SEDIAAN FACE MIST EKSTRAK DAUN ALPUKAT (Persea americana Mill.)

2025-08-06T14:06:10+08:00

Avocado leaves are known to contain various bioactive compounds such as flavonoids, saponins, tannins, alkaloids, and phenols that are beneficial for skin health. This study refers to several literatures indicating that avocado leaf extract (Persea americana Mill.) exhibits significant antioxidant and antibacterial activities, which is why it was used as the active ingredient in the preparation of face mist. The aim of this research was to determine the physical quality of face mist formulations made with avocado leaf extract at concentrations of 0% (F0), 5% (F1), 7.5% (F2), and 10% (F3). The study was conducted experimentally in the laboratory, where the avocado leaf extract was obtained through maceration using 96% ethanol as the solvent. Physical quality tests performed included organoleptic evaluation, homogeneity test, pH measurement, spray distribution test, drying time test, and viscosity test. The results showed that avocado leaf extract (Persea americana Mill.) can be formulated into face mist preparations at concentrations of 5%, 7.5%, and 10%, all of which met the physical quality standards for face mist products.